BDBM50000773 1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(3-fluoro-propyl)-piperazine::CHEMBL70540

SMILES: FCCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1

InChI Key: InChIKey=SYLQLALDNDYPPG-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50000773   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000773 (1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(3-fluoro-prop...) Show SMILES FCCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C15H21Cl2FN2/c16-14-3-2-13(12-15(14)17)4-7-20-10-8-19(9-11-20)6-1-5-18/h2-3,12H,1,4-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-pentazocine as radioligand.				J Med Chem 35: 2221-30 (1992) BindingDB Entry DOI: 10.7270/Q24B31ZD
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000773 (1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(3-fluoro-prop...) Show SMILES FCCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C15H21Cl2FN2/c16-14-3-2-13(12-15(14)17)4-7-20-10-8-19(9-11-20)6-1-5-18/h2-3,12H,1,4-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-pentazocine as radioligand.				J Med Chem 35: 2221-30 (1992) BindingDB Entry DOI: 10.7270/Q24B31ZD
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50000773 (1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(3-fluoro-prop...) Show SMILES FCCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C15H21Cl2FN2/c16-14-3-2-13(12-15(14)17)4-7-20-10-8-19(9-11-20)6-1-5-18/h2-3,12H,1,4-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity against dopamine receptor D2 from rat brain, using [3H](-)-sulpiride as radioligand.				J Med Chem 35: 2221-30 (1992) BindingDB Entry DOI: 10.7270/Q24B31ZD
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (RAT)	BDBM50000773 (1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(3-fluoro-prop...) Show SMILES FCCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C15H21Cl2FN2/c16-14-3-2-13(12-15(14)17)4-7-20-10-8-19(9-11-20)6-1-5-18/h2-3,12H,1,4-11H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	6.83E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity against muscarinic cholinergic receptor from rat brain, using [3H]-QNB as radioligand.				J Med Chem 35: 2221-30 (1992) BindingDB Entry DOI: 10.7270/Q24B31ZD
					More data for this Ligand-Target Pair