BDBM50000867 7-(4-Hydroxy-pentyloxy)-1,3-dihydro-imidazo[4,5-b]quinolin-2-one::CHEMBL91359
SMILES: CC(O)CCCOc1ccc2nc3[nH]c(=O)[nH]c3cc2c1
InChI Key: InChIKey=AOAQFGRPXBJZPI-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphodiesterase 3 (Homo sapiens (Human)) | BDBM50000867 (7-(4-Hydroxy-pentyloxy)-1,3-dihydro-imidazo[4,5-b]...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of platelet aggregation using adenosine diphosphate (ADP) as activating agent in human platelet rich plasma (PRP) | J Med Chem 35: 2672-87 (1992) BindingDB Entry DOI: 10.7270/Q2513X52 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase 4A (Sus scrofa) | BDBM50000867 (7-(4-Hydroxy-pentyloxy)-1,3-dihydro-imidazo[4,5-b]...) | UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 520 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of ADP-induced platelet aggregation in rabbit platelet rich plasma (PRP) | J Med Chem 35: 2672-87 (1992) BindingDB Entry DOI: 10.7270/Q2513X52 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Purinergic receptor P2Y12 (Homo sapiens (Human)) | BDBM50000867 (7-(4-Hydroxy-pentyloxy)-1,3-dihydro-imidazo[4,5-b]...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of platelet aggregation using adenosine diphosphate (ADP) as activating agent in human platelet rich plasma (PRP) | J Med Chem 35: 2672-87 (1992) BindingDB Entry DOI: 10.7270/Q2513X52 | |||||||||||
More data for this Ligand-Target Pair |