BDBM50000878 7-[3-(1H-Tetrazol-5-yl)-propoxy]-1,3-dihydro-imidazo[4,5-b]quinolin-2-one::CHEMBL88835

SMILES: O=c1[nH]c2cc3cc(OCCCc4nnn[nH]4)ccc3nc2[nH]1

InChI Key: InChIKey=VHMRDRDPCZRGKM-UHFFFAOYSA-N

Data: 1 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50000878   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-inhibited 3',5'-cyclic phosphodiesterase A/B (Homo sapiens (Human))	BDBM50000878 (7-[3-(1H-Tetrazol-5-yl)-propoxy]-1,3-dihydro-imida...) Show SMILES O=c1[nH]c2cc3cc(OCCCc4nnn[nH]4)ccc3nc2[nH]1 Show InChI InChI=1S/C14H13N7O2/c22-14-16-11-7-8-6-9(3-4-10(8)15-13(11)17-14)23-5-1-2-12-18-20-21-19-12/h3-4,6-7H,1-2,5H2,(H2,15,16,17,22)(H,18,19,20,21)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of platelet aggregation using Adenosine diphosphate (ADP) as activating agent in rabbit platelet rich plasma (PRP)				J Med Chem 35: 2672-87 (1992) BindingDB Entry DOI: 10.7270/Q2513X52
					More data for this Ligand-Target Pair
P2Y purinoceptor 12 (Homo sapiens (Human))	BDBM50000878 (7-[3-(1H-Tetrazol-5-yl)-propoxy]-1,3-dihydro-imida...) Show SMILES O=c1[nH]c2cc3cc(OCCCc4nnn[nH]4)ccc3nc2[nH]1 Show InChI InChI=1S/C14H13N7O2/c22-14-16-11-7-8-6-9(3-4-10(8)15-13(11)17-14)23-5-1-2-12-18-20-21-19-12/h3-4,6-7H,1-2,5H2,(H2,15,16,17,22)(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	6.32E+3	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of platelet aggregation using Adenosine diphosphate (ADP) as activating agent in rabbit platelet rich plasma (PRP)				J Med Chem 35: 2672-87 (1992) BindingDB Entry DOI: 10.7270/Q2513X52
					More data for this Ligand-Target Pair
P2Y purinoceptor 12 (Homo sapiens (Human))	BDBM50000878 (7-[3-(1H-Tetrazol-5-yl)-propoxy]-1,3-dihydro-imida...) Show SMILES O=c1[nH]c2cc3cc(OCCCc4nnn[nH]4)ccc3nc2[nH]1 Show InChI InChI=1S/C14H13N7O2/c22-14-16-11-7-8-6-9(3-4-10(8)15-13(11)17-14)23-5-1-2-12-18-20-21-19-12/h3-4,6-7H,1-2,5H2,(H2,15,16,17,22)(H,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of platelet aggregation using adenosine diphosphate (ADP) as activating agent in human platelet rich plasma (PRP)				J Med Chem 35: 2672-87 (1992) BindingDB Entry DOI: 10.7270/Q2513X52
					More data for this Ligand-Target Pair