BDBM50000886 4-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-yloxy)-butyric acid::CHEMBL313463

SMILES: OC(=O)CCCOc1ccc2nc3[nH]c(=O)[nH]c3cc2c1

InChI Key: InChIKey=XNHZEJRZFBXTOB-UHFFFAOYSA-N

Data: 2 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50000886   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human))	BDBM50000886 (4-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-y...) Show SMILES OC(=O)CCCOc1ccc2nc3[nH]c(=O)[nH]c3cc2c1 Show InChI InChI=1S/C14H13N3O4/c18-12(19)2-1-5-21-9-3-4-10-8(6-9)7-11-13(15-10)17-14(20)16-11/h3-4,6-7H,1-2,5H2,(H,18,19)(H2,15,16,17,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human platelet PDE by inhibiting cyclic Guanosine monophosphate (cGMP) hydrolysis				J Med Chem 35: 2672-87 (1992) BindingDB Entry DOI: 10.7270/Q2513X52
					More data for this Ligand-Target Pair
Phosphodiesterase 3 (Homo sapiens (Human))	BDBM50000886 (4-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-y...) Show SMILES OC(=O)CCCOc1ccc2nc3[nH]c(=O)[nH]c3cc2c1 Show InChI InChI=1S/C14H13N3O4/c18-12(19)2-1-5-21-9-3-4-10-8(6-9)7-11-13(15-10)17-14(20)16-11/h3-4,6-7H,1-2,5H2,(H,18,19)(H2,15,16,17,20)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human platelet PDE by inhibiting cyclic Adenosine monophosphate (cAMP) hydrolysis				J Med Chem 35: 2672-87 (1992) BindingDB Entry DOI: 10.7270/Q2513X52
					More data for this Ligand-Target Pair
Purinergic receptor P2Y12 (Homo sapiens (Human))	BDBM50000886 (4-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-y...) Show SMILES OC(=O)CCCOc1ccc2nc3[nH]c(=O)[nH]c3cc2c1 Show InChI InChI=1S/C14H13N3O4/c18-12(19)2-1-5-21-9-3-4-10-8(6-9)7-11-13(15-10)17-14(20)16-11/h3-4,6-7H,1-2,5H2,(H,18,19)(H2,15,16,17,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	1.04E+3	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of platelet aggregation using adenosine diphosphate (ADP) as activating agent in human platelet rich plasma (PRP)				J Med Chem 35: 2672-87 (1992) BindingDB Entry DOI: 10.7270/Q2513X52
					More data for this Ligand-Target Pair
Purinergic receptor P2Y12 (Homo sapiens (Human))	BDBM50000886 (4-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-y...) Show SMILES OC(=O)CCCOc1ccc2nc3[nH]c(=O)[nH]c3cc2c1 Show InChI InChI=1S/C14H13N3O4/c18-12(19)2-1-5-21-9-3-4-10-8(6-9)7-11-13(15-10)17-14(20)16-11/h3-4,6-7H,1-2,5H2,(H,18,19)(H2,15,16,17,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of platelet aggregation using Adenosine diphosphate (ADP) as activating agent in rabbit platelet rich plasma (PRP)				J Med Chem 35: 2672-87 (1992) BindingDB Entry DOI: 10.7270/Q2513X52
					More data for this Ligand-Target Pair