null

SMILES: OC(=O)CCCCOc1ccc2nc3[nH]c(=O)[nH]c3cc2c1

InChI Key: InChIKey=AHNFHVODVZRNNS-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50000889   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2Y purinoceptor 12 (Homo sapiens (Human))	BDBM50000889 (5-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-y...) Show SMILES OC(=O)CCCCOc1ccc2nc3[nH]c(=O)[nH]c3cc2c1 Show InChI InChI=1S/C15H15N3O4/c19-13(20)3-1-2-6-22-10-4-5-11-9(7-10)8-12-14(16-11)18-15(21)17-12/h4-5,7-8H,1-3,6H2,(H,19,20)(H2,16,17,18,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	>1.06E+5	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of platelet aggregation using Adenosine diphosphate (ADP) as activating agent in rabbit platelet rich plasma (PRP)				J Med Chem 35: 2672-87 (1992) BindingDB Entry DOI: 10.7270/Q2513X52
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50000889 (5-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-y...) Show SMILES OC(=O)CCCCOc1ccc2nc3[nH]c(=O)[nH]c3cc2c1 Show InChI InChI=1S/C15H15N3O4/c19-13(20)3-1-2-6-22-10-4-5-11-9(7-10)8-12-14(16-11)18-15(21)17-12/h4-5,7-8H,1-3,6H2,(H,19,20)(H2,16,17,18,21)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human platelet PDE by inhibiting cyclic Adenosine monophosphate (cAMP) hydrolysis				J Med Chem 35: 2672-87 (1992) BindingDB Entry DOI: 10.7270/Q2513X52
					More data for this Ligand-Target Pair
P2Y purinoceptor 12 (Homo sapiens (Human))	BDBM50000889 (5-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-y...) Show SMILES OC(=O)CCCCOc1ccc2nc3[nH]c(=O)[nH]c3cc2c1 Show InChI InChI=1S/C15H15N3O4/c19-13(20)3-1-2-6-22-10-4-5-11-9(7-10)8-12-14(16-11)18-15(21)17-12/h4-5,7-8H,1-3,6H2,(H,19,20)(H2,16,17,18,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	>1.06E+5	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of platelet aggregation using adenosine diphosphate (ADP) as activating agent in human platelet rich plasma (PRP)				J Med Chem 35: 2672-87 (1992) BindingDB Entry DOI: 10.7270/Q2513X52
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50000889 (5-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-y...) Show SMILES OC(=O)CCCCOc1ccc2nc3[nH]c(=O)[nH]c3cc2c1 Show InChI InChI=1S/C15H15N3O4/c19-13(20)3-1-2-6-22-10-4-5-11-9(7-10)8-12-14(16-11)18-15(21)17-12/h4-5,7-8H,1-3,6H2,(H,19,20)(H2,16,17,18,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human platelet PDE by inhibiting cyclic Guanosine monophosphate (cGMP) hydrolysis				J Med Chem 35: 2672-87 (1992) BindingDB Entry DOI: 10.7270/Q2513X52
					More data for this Ligand-Target Pair