BDBM50000891 5-(1-Methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-yloxy)-pentanoic acid cycloheptyl-methyl-amide::CHEMBL88764

SMILES: CN(C1CCCCCC1)C(=O)CCCCOc1ccc2nc3[nH]c(=O)n(C)c3cc2c1

InChI Key: InChIKey=NAPKHDRXTZVUOK-UHFFFAOYSA-N

Data: 2 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50000891   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 3 (Homo sapiens (Human))	BDBM50000891 (5-(1-Methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]qui...) Show SMILES CN(C1CCCCCC1)C(=O)CCCCOc1ccc2nc3[nH]c(=O)n(C)c3cc2c1 Show InChI InChI=1S/C24H32N4O3/c1-27(18-9-5-3-4-6-10-18)22(29)11-7-8-14-31-19-12-13-20-17(15-19)16-21-23(25-20)26-24(30)28(21)2/h12-13,15-16,18H,3-11,14H2,1-2H3,(H,25,26,30)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of platelet aggregation using Adenosine diphosphate (ADP) as activating agent in rabbit platelet rich plasma (PRP)				J Med Chem 35: 2672-87 (1992) BindingDB Entry DOI: 10.7270/Q2513X52
					More data for this Ligand-Target Pair
Purinergic receptor P2Y12 (Homo sapiens (Human))	BDBM50000891 (5-(1-Methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]qui...) Show SMILES CN(C1CCCCCC1)C(=O)CCCCOc1ccc2nc3[nH]c(=O)n(C)c3cc2c1 Show InChI InChI=1S/C24H32N4O3/c1-27(18-9-5-3-4-6-10-18)22(29)11-7-8-14-31-19-12-13-20-17(15-19)16-21-23(25-20)26-24(30)28(21)2/h12-13,15-16,18H,3-11,14H2,1-2H3,(H,25,26,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of platelet aggregation using Adenosine diphosphate (ADP) as activating agent in rabbit platelet rich plasma (PRP)				J Med Chem 35: 2672-87 (1992) BindingDB Entry DOI: 10.7270/Q2513X52
					More data for this Ligand-Target Pair
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human))	BDBM50000891 (5-(1-Methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]qui...) Show SMILES CN(C1CCCCCC1)C(=O)CCCCOc1ccc2nc3[nH]c(=O)n(C)c3cc2c1 Show InChI InChI=1S/C24H32N4O3/c1-27(18-9-5-3-4-6-10-18)22(29)11-7-8-14-31-19-12-13-20-17(15-19)16-21-23(25-20)26-24(30)28(21)2/h12-13,15-16,18H,3-11,14H2,1-2H3,(H,25,26,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human platelet PDE by inhibiting cyclic Guanosine monophosphate (cGMP) hydrolysis				J Med Chem 35: 2672-87 (1992) BindingDB Entry DOI: 10.7270/Q2513X52
					More data for this Ligand-Target Pair
Purinergic receptor P2Y12 (Homo sapiens (Human))	BDBM50000891 (5-(1-Methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]qui...) Show SMILES CN(C1CCCCCC1)C(=O)CCCCOc1ccc2nc3[nH]c(=O)n(C)c3cc2c1 Show InChI InChI=1S/C24H32N4O3/c1-27(18-9-5-3-4-6-10-18)22(29)11-7-8-14-31-19-12-13-20-17(15-19)16-21-23(25-20)26-24(30)28(21)2/h12-13,15-16,18H,3-11,14H2,1-2H3,(H,25,26,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	540	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of platelet aggregation using adenosine diphosphate (ADP) as activating agent in human platelet rich plasma (PRP)				J Med Chem 35: 2672-87 (1992) BindingDB Entry DOI: 10.7270/Q2513X52
					More data for this Ligand-Target Pair