BDBM50000907 4-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-yloxy)-butyronitrile::CHEMBL92269

SMILES: O=c1[nH]c2cc3cc(OCCCC#N)ccc3nc2[nH]1

InChI Key: InChIKey=SQQQFLSWQVAOHA-UHFFFAOYSA-N

Data: 1 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50000907   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Purinergic receptor P2Y12 (Homo sapiens (Human))	BDBM50000907 (4-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-y...) Show SMILES O=c1[nH]c2cc3cc(OCCCC#N)ccc3nc2[nH]1 Show InChI InChI=1S/C14H12N4O2/c15-5-1-2-6-20-10-3-4-11-9(7-10)8-12-13(16-11)18-14(19)17-12/h3-4,7-8H,1-2,6H2,(H2,16,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	600	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of platelet aggregation using adenosine diphosphate (ADP) as activating agent in human platelet rich plasma (PRP)				J Med Chem 35: 2672-87 (1992) BindingDB Entry DOI: 10.7270/Q2513X52
					More data for this Ligand-Target Pair
Phosphodiesterase 3 (Homo sapiens (Human))	BDBM50000907 (4-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-y...) Show SMILES O=c1[nH]c2cc3cc(OCCCC#N)ccc3nc2[nH]1 Show InChI InChI=1S/C14H12N4O2/c15-5-1-2-6-20-10-3-4-11-9(7-10)8-12-13(16-11)18-14(19)17-12/h3-4,7-8H,1-2,6H2,(H2,16,17,18,19)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human platelet PDE by inhibiting cyclic Adenosine monophosphate (cAMP) hydrolysis				J Med Chem 35: 2672-87 (1992) BindingDB Entry DOI: 10.7270/Q2513X52
					More data for this Ligand-Target Pair
Purinergic receptor P2Y12 (Homo sapiens (Human))	BDBM50000907 (4-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-y...) Show SMILES O=c1[nH]c2cc3cc(OCCCC#N)ccc3nc2[nH]1 Show InChI InChI=1S/C14H12N4O2/c15-5-1-2-6-20-10-3-4-11-9(7-10)8-12-13(16-11)18-14(19)17-12/h3-4,7-8H,1-2,6H2,(H2,16,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	180	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of platelet aggregation using Adenosine diphosphate (ADP) as activating agent in rabbit platelet rich plasma (PRP)				J Med Chem 35: 2672-87 (1992) BindingDB Entry DOI: 10.7270/Q2513X52
					More data for this Ligand-Target Pair