BDBM50001003 CHEMBL3235686

SMILES: CCC[Si](CCC)(c1ccc(O)c(C)c1)c1ccc(O)c(C)c1

InChI Key: InChIKey=WIRHVWGXFGRIGT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50001003   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estradiol receptor beta (ERβ) (Homo sapiens (Human))	BDBM50001003 (CHEMBL3235686) Show SMILES CCC[Si](CCC)(c1ccc(O)c(C)c1)c1ccc(O)c(C)c1 Show InChI InChI=1S/C20H28O2Si/c1-5-11-23(12-6-2,17-7-9-19(21)15(3)13-17)18-8-10-20(22)16(4)14-18/h7-10,13-14,21-22H,5-6,11-12H2,1-4H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	804	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at human Gal4-fused ER-beta expressed in HEK293 cells assessed as inhibition of 17beta-estradiol-induced effect by luciferase rep...				Bioorg Med Chem 22: 2244-52 (2014) Article DOI: 10.1016/j.bmc.2014.02.025 BindingDB Entry DOI: 10.7270/Q2H996QP
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50001003 (CHEMBL3235686) Show SMILES CCC[Si](CCC)(c1ccc(O)c(C)c1)c1ccc(O)c(C)c1 Show InChI InChI=1S/C20H28O2Si/c1-5-11-23(12-6-2,17-7-9-19(21)15(3)13-17)18-8-10-20(22)16(4)14-18/h7-10,13-14,21-22H,5-6,11-12H2,1-4H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at human Gal4-fused ER-alpha expressed in HEK293 cells assessed as inhibition of 17beta-estradiol-induced effect by luciferase re...				Bioorg Med Chem 22: 2244-52 (2014) Article DOI: 10.1016/j.bmc.2014.02.025 BindingDB Entry DOI: 10.7270/Q2H996QP
					More data for this Ligand-Target Pair