BDBM50001610 7-[3-(4-Acetyl-3-methoxy-2-propyl-phenoxy)-propoxy]-8-propyl-chroman-2-carboxylic acid::7-[3-(4-Acetyl-3-methoxy-2-propyl-phenoxy)-propoxy]-8-propyl-chroman-2-carboxylic acid (SC41930)::CGS 24115::CHEMBL14823::SC-41930
SMILES: CCCc1c(OCCCOc2ccc3CCC(Oc3c2CCC)C(O)=O)ccc(C(C)=O)c1OC
InChI Key: InChIKey=ZVVCSBSDFGYRCB-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50001610 (7-[3-(4-Acetyl-3-methoxy-2-propyl-phenoxy)-propoxy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Inhibition of specific binding of [3H]-LTB4 to LTB4 receptor in guinea pig lung membranes | Citation and Details BindingDB Entry DOI: 10.7270/Q23N25HN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene 2 (Homo sapiens (Human)) | BDBM50001610 (7-[3-(4-Acetyl-3-methoxy-2-propyl-phenoxy)-propoxy...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 131 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by PDSP Ki Database | J Pharmacol Exp Ther 262: 80-9 (1992) BindingDB Entry DOI: 10.7270/Q21C1VBX | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene 2 (Homo sapiens (Human)) | BDBM50001610 (7-[3-(4-Acetyl-3-methoxy-2-propyl-phenoxy)-propoxy...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 137 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by PDSP Ki Database | J Pharmacol Exp Ther 262: 80-9 (1992) BindingDB Entry DOI: 10.7270/Q21C1VBX | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50001610 (7-[3-(4-Acetyl-3-methoxy-2-propyl-phenoxy)-propoxy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Smithkline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity against Leukotriene B4 receptor on intact differentiated U-937 cells in competitive binding assay with [3H]-LTB4 | J Med Chem 36: 3333-40 (1993) BindingDB Entry DOI: 10.7270/Q2BG2N1M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50001610 (7-[3-(4-Acetyl-3-methoxy-2-propyl-phenoxy)-propoxy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | 280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro antagonist activity against leukotriene B4 (LTB4) receptor in [3H]-LTB4 human neutrophil receptor binding assay | Bioorg Med Chem Lett 5: 887-892 (1995) Article DOI: 10.1016/0960-894X(95)00135-G BindingDB Entry DOI: 10.7270/Q2J966BX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50001610 (7-[3-(4-Acetyl-3-methoxy-2-propyl-phenoxy)-propoxy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against leukotriene B4 receptor | Bioorg Med Chem Lett 4: 811-816 (1994) Article DOI: 10.1016/S0960-894X(01)80853-2 BindingDB Entry DOI: 10.7270/Q2DN451X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50001610 (7-[3-(4-Acetyl-3-methoxy-2-propyl-phenoxy)-propoxy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against LTB4 (leukotriene) binding | J Med Chem 39: 2629-54 (1996) Article DOI: 10.1021/jm960088k BindingDB Entry DOI: 10.7270/Q21J9BFT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50001610 (7-[3-(4-Acetyl-3-methoxy-2-propyl-phenoxy)-propoxy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced Chemotaxis | Bioorg Med Chem Lett 5: 887-892 (1995) Article DOI: 10.1016/0960-894X(95)00135-G BindingDB Entry DOI: 10.7270/Q2J966BX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50001610 (7-[3-(4-Acetyl-3-methoxy-2-propyl-phenoxy)-propoxy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibitory concentration against leukotriene receptor B4 (LTB4) in human polymorphonuclear cells (PMNs) | J Med Chem 36: 2703-5 (1993) BindingDB Entry DOI: 10.7270/Q2HQ3XZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50001610 (7-[3-(4-Acetyl-3-methoxy-2-propyl-phenoxy)-propoxy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Inhibition of specific binding of [3H]LTB4 to LTB4 receptor in human neutrophils | Citation and Details BindingDB Entry DOI: 10.7270/Q23N25HN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50001610 (7-[3-(4-Acetyl-3-methoxy-2-propyl-phenoxy)-propoxy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Research and Development Curated by ChEMBL | Assay Description Binding affinity of the compound towards Leukotriene B4 (LTB4) Receptor. (Experiment conducted in the absence of NDGA) | J Med Chem 38: 858-68 (1995) BindingDB Entry DOI: 10.7270/Q22806N0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50001610 (7-[3-(4-Acetyl-3-methoxy-2-propyl-phenoxy)-propoxy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
G.D. Searle and Co. Curated by ChEMBL | Assay Description Compound was evaluated in a human neutrophil leukotriene B4 receptor binding assay | J Med Chem 32: 1145-7 (1989) BindingDB Entry DOI: 10.7270/Q2XK8DJ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50001610 (7-[3-(4-Acetyl-3-methoxy-2-propyl-phenoxy)-propoxy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhone-Poulenc Rorer Central Research Curated by ChEMBL | Assay Description Concentration of the compound inhibiting the binding of [3H]-LTB4 to human neutrophils | J Med Chem 35: 4253-5 (1992) BindingDB Entry DOI: 10.7270/Q208648W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50001610 (7-[3-(4-Acetyl-3-methoxy-2-propyl-phenoxy)-propoxy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Research and Development Curated by ChEMBL | Assay Description Binding affinity for Leukotriene B4 (LTB4) receptor | J Med Chem 38: 858-68 (1995) BindingDB Entry DOI: 10.7270/Q22806N0 | |||||||||||
More data for this Ligand-Target Pair |