BDBM50001637 6-[4-(3-Methoxy-phenyl)-6-phenyl-pyridin-2-yloxy]-2-methyl-hexanoic acid::CHEMBL137336
SMILES: COc1cccc(c1)-c1cc(OCCCCC(C)C(O)=O)nc(c1)-c1ccccc1
InChI Key: InChIKey=CLCYPUVDBPCOQP-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50001637 (6-[4-(3-Methoxy-phenyl)-6-phenyl-pyridin-2-yloxy]-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherche de Vitry-Alfortville Curated by ChEMBL | Assay Description Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes | J Med Chem 35: 4315-24 (1992) BindingDB Entry DOI: 10.7270/Q2QR4W2W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50001637 (6-[4-(3-Methoxy-phenyl)-6-phenyl-pyridin-2-yloxy]-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherche de Vitry-Alfortville Curated by ChEMBL | Assay Description Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes. | J Med Chem 35: 4315-24 (1992) BindingDB Entry DOI: 10.7270/Q2QR4W2W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50001637 (6-[4-(3-Methoxy-phenyl)-6-phenyl-pyridin-2-yloxy]-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherche de Vitry-Alfortville Curated by ChEMBL | Assay Description Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes. | J Med Chem 35: 4315-24 (1992) BindingDB Entry DOI: 10.7270/Q2QR4W2W | |||||||||||
More data for this Ligand-Target Pair |