BDBM50001645 6-[6-(2-Fluoro-phenyl)-4-phenyl-pyridin-2-yloxy]-2-methyl-hexanoic acid::CHEMBL344230

SMILES: CC(CCCCOc1cc(cc(n1)-c1ccccc1F)-c1ccccc1)C(O)=O

InChI Key: InChIKey=XHRNNMAQJJKUCE-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001645   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene B4 receptor (Homo sapiens (Human))	BDBM50001645 (6-[6-(2-Fluoro-phenyl)-4-phenyl-pyridin-2-yloxy]-2...) Show SMILES CC(CCCCOc1cc(cc(n1)-c1ccccc1F)-c1ccccc1)C(O)=O Show InChI InChI=1S/C24H24FNO3/c1-17(24(27)28)9-7-8-14-29-23-16-19(18-10-3-2-4-11-18)15-22(26-23)20-12-5-6-13-21(20)25/h2-6,10-13,15-17H,7-9,14H2,1H3,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche de Vitry-Alfortville Curated by ChEMBL					Assay Description Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytes				J Med Chem 35: 4315-24 (1992) BindingDB Entry DOI: 10.7270/Q2QR4W2W
					More data for this Ligand-Target Pair
Leukotriene B4 receptor (Homo sapiens (Human))	BDBM50001645 (6-[6-(2-Fluoro-phenyl)-4-phenyl-pyridin-2-yloxy]-2...) Show SMILES CC(CCCCOc1cc(cc(n1)-c1ccccc1F)-c1ccccc1)C(O)=O Show InChI InChI=1S/C24H24FNO3/c1-17(24(27)28)9-7-8-14-29-23-16-19(18-10-3-2-4-11-18)15-22(26-23)20-12-5-6-13-21(20)25/h2-6,10-13,15-17H,7-9,14H2,1H3,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche de Vitry-Alfortville Curated by ChEMBL					Assay Description Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.				J Med Chem 35: 4315-24 (1992) BindingDB Entry DOI: 10.7270/Q2QR4W2W
					More data for this Ligand-Target Pair
Leukotriene B4 receptor (Homo sapiens (Human))	BDBM50001645 (6-[6-(2-Fluoro-phenyl)-4-phenyl-pyridin-2-yloxy]-2...) Show SMILES CC(CCCCOc1cc(cc(n1)-c1ccccc1F)-c1ccccc1)C(O)=O Show InChI InChI=1S/C24H24FNO3/c1-17(24(27)28)9-7-8-14-29-23-16-19(18-10-3-2-4-11-18)15-22(26-23)20-12-5-6-13-21(20)25/h2-6,10-13,15-17H,7-9,14H2,1H3,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche de Vitry-Alfortville Curated by ChEMBL					Assay Description Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.				J Med Chem 35: 4315-24 (1992) BindingDB Entry DOI: 10.7270/Q2QR4W2W
					More data for this Ligand-Target Pair