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BDBM50001734 CHEMBL3238103

SMILES: COc1cc(Nc2ccnc3[nH]c4ccccc4c23)ccc1Br

InChI Key: InChIKey=XGALLOCAQCEKSU-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50001734   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase BRK


(Homo sapiens (Human))
BDBM50001734
PNG
(CHEMBL3238103)
Show SMILES COc1cc(Nc2ccnc3[nH]c4ccccc4c23)ccc1Br
Show InChI InChI=1S/C18H14BrN3O/c1-23-16-10-11(6-7-13(16)19)21-15-8-9-20-18-17(15)12-4-2-3-5-14(12)22-18/h2-10H,1H3,(H2,20,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.40n/an/an/an/an/an/a



Martin-Luther University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of Brk (unknown origin) using [gamma-33P]-ATP after 60 mins by scintillation counting


Bioorg Med Chem Lett 24: 1948-51 (2014)


Article DOI: 10.1016/j.bmcl.2014.03.002
BindingDB Entry DOI: 10.7270/Q2TM7CN0
More data for this
Ligand-Target Pair