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BDBM50001736 CHEMBL3238096

SMILES: C(Oc1cccc(Nc2ccnc3[nH]c4ccccc4c23)c1)c1ccccc1

InChI Key: InChIKey=KXFOQJAXINULOV-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50001736   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase BRK


(Homo sapiens (Human))
BDBM50001736
PNG
(CHEMBL3238096)
Show SMILES C(Oc1cccc(Nc2ccnc3[nH]c4ccccc4c23)c1)c1ccccc1
Show InChI InChI=1S/C24H19N3O/c1-2-7-17(8-3-1)16-28-19-10-6-9-18(15-19)26-22-13-14-25-24-23(22)20-11-4-5-12-21(20)27-24/h1-15H,16H2,(H2,25,26,27)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 41n/an/an/an/an/an/a



Martin-Luther University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of Brk (unknown origin) using [gamma-33P]-ATP after 60 mins by scintillation counting


Bioorg Med Chem Lett 24: 1948-51 (2014)


Article DOI: 10.1016/j.bmcl.2014.03.002
BindingDB Entry DOI: 10.7270/Q2TM7CN0
More data for this
Ligand-Target Pair