BDBM50001737 CHEMBL3238091
SMILES: C1C=CCc2cc(Nc3ccnc4[nH]c5ccccc5c34)ccc12
InChI Key: InChIKey=SPSWKAIKWUDSIR-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase BRK (Homo sapiens (Human)) | BDBM50001737 (CHEMBL3238091) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther University Halle-Wittenberg Curated by ChEMBL | Assay Description Inhibition of Brk (unknown origin) using [gamma-33P]-ATP after 60 mins by scintillation counting | Bioorg Med Chem Lett 24: 1948-51 (2014) Article DOI: 10.1016/j.bmcl.2014.03.002 BindingDB Entry DOI: 10.7270/Q2TM7CN0 | |||||||||||
More data for this Ligand-Target Pair |