null
SMILES: Cc1nnc(-c2cccnc2)n1-c1ccc(OCCCN2CCCCC2)cc1
InChI Key: InChIKey=PWBFJEIJPADHLX-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50001752 (CHEMBL3238445) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 0.240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
United Arab Emirates University Curated by ChEMBL | Assay Description Displacement of [3H]N-alpha-methylhistamine from human H3 receptor expressed in HEK-293 cell membrane after 90 mins by liquid scintillation counting ... | Eur J Med Chem 77: 269-79 (2014) Article DOI: 10.1016/j.ejmech.2014.03.014 BindingDB Entry DOI: 10.7270/Q29K4CR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H1 receptor (Homo sapiens (Human)) | BDBM50001752 (CHEMBL3238445) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 1.05E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
United Arab Emirates University Curated by ChEMBL | Assay Description Displacement of [3H]pyrilamine from human H1 receptor expressed in CHO cell membrane after 120 mins by liquid scintillation counting analysis | Eur J Med Chem 77: 269-79 (2014) Article DOI: 10.1016/j.ejmech.2014.03.014 BindingDB Entry DOI: 10.7270/Q29K4CR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H4 receptor (Homo sapiens (Human)) | BDBM50001752 (CHEMBL3238445) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 1.41E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
United Arab Emirates University Curated by ChEMBL | Assay Description Displacement of [3H]histamine from human H4 receptor expressed in Sf9 cell membrane co-transfected with Galphai2 and Gbeta1gamma2 after 60 mins by li... | Eur J Med Chem 77: 269-79 (2014) Article DOI: 10.1016/j.ejmech.2014.03.014 BindingDB Entry DOI: 10.7270/Q29K4CR6 | |||||||||||
More data for this Ligand-Target Pair |