BDBM50002035 (2-Hydroxycarbamoyl-3-phenyl-propionylamino)-acetic acid::(R,S)(2-Hydroxycarbamoyl-3-phenyl-propionylamino)-acetic acid::CHEMBL17107

SMILES: ONC(=O)C(Cc1ccccc1)C(=O)NCC(O)=O

InChI Key: InChIKey=GVBPRTLYHQOKRI-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50002035   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50002035 ((2-Hydroxycarbamoyl-3-phenyl-propionylamino)-aceti...) Show SMILES ONC(=O)C(Cc1ccccc1)C(=O)NCC(O)=O Show InChI InChI=1S/C12H14N2O5/c15-10(16)7-13-11(17)9(12(18)14-19)6-8-4-2-1-3-5-8/h1-5,9,19H,6-7H2,(H,13,17)(H,14,18)(H,15,16)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
UA 498 CNRS Curated by ChEMBL					Assay Description Inhibition of [3H]Ala2-Leu-enkephalin binding to Neutral endopeptidase (NEP)				J Med Chem 31: 1825-31 (1988) BindingDB Entry DOI: 10.7270/Q2R49RC8
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50002035 ((2-Hydroxycarbamoyl-3-phenyl-propionylamino)-aceti...) Show SMILES ONC(=O)C(Cc1ccccc1)C(=O)NCC(O)=O Show InChI InChI=1S/C12H14N2O5/c15-10(16)7-13-11(17)9(12(18)14-19)6-8-4-2-1-3-5-8/h1-5,9,19H,6-7H2,(H,13,17)(H,14,18)(H,15,16)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory potency against neutral endopeptidase				J Med Chem 35: 1259-66 (1992) BindingDB Entry DOI: 10.7270/Q2125T81
					More data for this Ligand-Target Pair
Neutral Endopeptidase (NEP) (Rattus norvegicus (Rat))	BDBM50002035 ((2-Hydroxycarbamoyl-3-phenyl-propionylamino)-aceti...) Show SMILES ONC(=O)C(Cc1ccccc1)C(=O)NCC(O)=O Show InChI InChI=1S/C12H14N2O5/c15-10(16)7-13-11(17)9(12(18)14-19)6-8-4-2-1-3-5-8/h1-5,9,19H,6-7H2,(H,13,17)(H,14,18)(H,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of enkephalinase purified from rat kidney.				J Med Chem 28: 1158-69 (1985) BindingDB Entry DOI: 10.7270/Q20C4WB5
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50002035 ((2-Hydroxycarbamoyl-3-phenyl-propionylamino)-aceti...) Show SMILES ONC(=O)C(Cc1ccccc1)C(=O)NCC(O)=O Show InChI InChI=1S/C12H14N2O5/c15-10(16)7-13-11(17)9(12(18)14-19)6-8-4-2-1-3-5-8/h1-5,9,19H,6-7H2,(H,13,17)(H,14,18)(H,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against rabbit kidney aminopeptidase using 10 nM of [3H]Leu-enkephalin as substrate				J Med Chem 28: 1158-69 (1985) BindingDB Entry DOI: 10.7270/Q20C4WB5
					More data for this Ligand-Target Pair