BDBM50002288 1-(4-Fluoro-phenyl)-2-{1-[2-(4-trifluoromethyl-phenyl)-ethyl]-piperidin-4-yl}-ethanone::CHEMBL136794
SMILES: Fc1ccc(cc1)C(=O)CC1CCN(CCc2ccc(cc2)C(F)(F)F)CC1
InChI Key: InChIKey=JXDNMESNLICMIF-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serotonin 2 (5-HT2) receptor (Mus musculus (Mouse)) | BDBM50002288 (1-(4-Fluoro-phenyl)-2-{1-[2-(4-trifluoromethyl-phe...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002288 (1-(4-Fluoro-phenyl)-2-{1-[2-(4-trifluoromethyl-phe...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Mus musculus (Mouse)) | BDBM50002288 (1-(4-Fluoro-phenyl)-2-{1-[2-(4-trifluoromethyl-phe...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity towards dopamine receptor D2 | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair |