BDBM50002370 (R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-propionic acid::(RS)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)-propionicacid::2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propionic acid::2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propionic acid(DL-AMPA)::2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)-propionic acid::2-amino-3-(5-methyl-3-oxo-2,3-dihydroisoxazol-4-yl)propanoic acid::2-ammonio-3-(3-hydroxy-5-methylisoxazol-4-yl)propanoate::AMPA::CHEMBL13378
SMILES: Cc1o[nH]c(=O)c1CC(N)C(O)=O
InChI Key: InChIKey=UUDAMDVQRQNNHZ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate receptor ionotropic, AMPA 2 (Rattus norvegicus) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.0170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat recombinant GluR2 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GRIA3 (RAT) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.0210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat recombinant GluR3 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 1 (Rattus norvegicus (Rat)) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.0220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat recombinant GluR1 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, AMPA 4 (Rattus norvegicus) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat recombinant GluR4 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (RAT) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]SYM 2081 from rat recombinant GluR5 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GRIA3 (Homo sapiens (Human)) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SIBIA Neurosciences, Inc. Curated by PDSP Ki Database | J Pharmacol Exp Ther 285: 358-70 (1998) BindingDB Entry DOI: 10.7270/Q23R0RDM | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, AMPA 2 (Rattus norvegicus) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 16.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
European Research Centre for Drug Discovery and Development (NatSynDrugs) Curated by ChEMBL | Assay Description Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR2(R) expressed in Sf9 cells | J Med Chem 51: 6614-8 (2008) Article DOI: 10.1021/jm800865a BindingDB Entry DOI: 10.7270/Q261117R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GRIA2 (Homo sapiens (Human)) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Binding affinity of compound was determined towards cloned Ionotropic glutamate receptor AMPA 2 (GluR2) expressed in Sf 9 insect cells | J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GRIA3 (RAT) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SIBIA Neurosciences, Inc. Curated by PDSP Ki Database | J Pharmacol Exp Ther 285: 358-70 (1998) BindingDB Entry DOI: 10.7270/Q23R0RDM | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GRIA3 (RAT) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 20.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
European Research Centre for Drug Discovery and Development (NatSynDrugs) Curated by ChEMBL | Assay Description Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR3 expressed in Sf9 cells | J Med Chem 51: 6614-8 (2008) Article DOI: 10.1021/jm800865a BindingDB Entry DOI: 10.7270/Q261117R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic AMPA (Homo sapiens (Human)) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Binding affinity of compound was determined towards cloned Ionotropic glutamate receptor AMPA 3 (GluR3) expressed in Sf 9 insect cells | J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 1 (Rattus norvegicus (Rat)) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 21.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
European Research Centre for Drug Discovery and Development (NatSynDrugs) Curated by ChEMBL | Assay Description Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR1 expressed in Sf9 cells | J Med Chem 51: 6614-8 (2008) Article DOI: 10.1021/jm800865a BindingDB Entry DOI: 10.7270/Q261117R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GRIA1 (Homo sapiens (Human)) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Binding affinity of compound was determined towards cloned Ionotropic glutamate receptor AMPA 1 (GluR1) expressed in Sf 9 insect cells | J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GRIA3 (RAT) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by PDSP Ki Database | Chirality 13: 523-32 (2001) Article DOI: 10.1002/chir.1172 BindingDB Entry DOI: 10.7270/Q2Z31X6K | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GRIA3 (RAT) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Royal Danish School of Pharmacy Curated by PDSP Ki Database | Eur J Pharmacol 189: 381-91 (1990) Article DOI: 10.1016/0922-4106(90)90035-v BindingDB Entry DOI: 10.7270/Q2MW2FNT | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, AMPA 4 (Rattus norvegicus) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
European Research Centre for Drug Discovery and Development (NatSynDrugs) Curated by ChEMBL | Assay Description Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR4 expressed in Sf9 cells | J Med Chem 51: 6614-8 (2008) Article DOI: 10.1021/jm800865a BindingDB Entry DOI: 10.7270/Q261117R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic AMPA (Homo sapiens (Human)) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Binding affinity of compound was determined towards cloned Ionotropic glutamate receptor AMPA 4 (GluR4) expressed in Sf 9 insect cells | J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
GRIK1 (Homo sapiens (Human)) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 740 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Binding affinity of compound was determined towards cloned Ionotropic glutamate receptor ionotropic kainate 1 (GluR5) expressed in Sf 9 insect cells | J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ionotropic glutamate receptor kainate 2/5 (Rattus norvegicus) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]KA from rat recombinant GluR6 expressed in Sf9 cells | J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (RAT) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
European Research Centre for Drug Discovery and Development (NatSynDrugs) Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR5(Q)1b expressed in Sf9 cells | J Med Chem 51: 6614-8 (2008) Article DOI: 10.1021/jm800865a BindingDB Entry DOI: 10.7270/Q261117R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GRIK4 (Homo sapiens (Human)) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.97E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Allelix Biopharmaceuticals, Inc. Curated by PDSP Ki Database | J Neurochem 62: 1-9 (1994) Article DOI: 10.1046/j.1471-4159.1994.62010001.x BindingDB Entry DOI: 10.7270/Q2RJ4H0P | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GRIA3 (RAT) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Royal Danish School of Pharmacy Curated by PDSP Ki Database | Eur J Pharmacol 189: 381-91 (1990) Article DOI: 10.1016/0922-4106(90)90035-v BindingDB Entry DOI: 10.7270/Q2MW2FNT | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GRIA3 (RAT) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Royal Danish School of Pharmacy Curated by PDSP Ki Database | Eur J Pharmacol 189: 381-91 (1990) Article DOI: 10.1016/0922-4106(90)90035-v BindingDB Entry DOI: 10.7270/Q2MW2FNT | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (Homo sapiens (Human)) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Curated by PDSP Ki Database | J Neurochem 75: 2590-601 (2000) Article DOI: 10.1046/j.1471-4159.2000.0752590.x BindingDB Entry DOI: 10.7270/Q2J67FGZ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (RAT) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by PDSP Ki Database | Eur J Pharmacol 411: 245-53 (2001) Article DOI: 10.1016/s0014-2999(00)00916-x BindingDB Entry DOI: 10.7270/Q2G73C8N | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GRIA3 (Homo sapiens (Human)) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SIBIA Neurosciences, Inc. Curated by PDSP Ki Database | J Pharmacol Exp Ther 285: 358-70 (1998) BindingDB Entry DOI: 10.7270/Q23R0RDM | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by PDSP Ki Database | Chirality 13: 523-32 (2001) Article DOI: 10.1002/chir.1172 BindingDB Entry DOI: 10.7270/Q2Z31X6K | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Curated by PDSP Ki Database | J Neurochem 75: 2590-601 (2000) Article DOI: 10.1046/j.1471-4159.2000.0752590.x BindingDB Entry DOI: 10.7270/Q2J67FGZ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (RAT) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by PDSP Ki Database | Chirality 13: 523-32 (2001) Article DOI: 10.1002/chir.1172 BindingDB Entry DOI: 10.7270/Q2Z31X6K | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by PDSP Ki Database | Eur J Pharmacol 411: 245-53 (2001) Article DOI: 10.1016/s0014-2999(00)00916-x BindingDB Entry DOI: 10.7270/Q2G73C8N | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human)) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Binding affinity of compound was determined towards cloned Ionotropic glutamate receptor ionotropic kainate 6 (GluR6) expressed in Sf 9 insect cells | J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NMDA receptor subunit 2C (GluN2C) (Rattus norvegicus (Rat)) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Binding affinity of compound was determined against N-methyl-D-aspartate glutamate receptor, using radioligand [3H]- CGP-39653 | J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ionotropic glutamate receptor kainate 2/5 (Rattus norvegicus) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
European Research Centre for Drug Discovery and Development (NatSynDrugs) Curated by ChEMBL | Assay Description Displacement of [3H]kainic acid from rat recombinant iGluR6(V,C,R) receptor expressed in Sf9 cells | J Med Chem 51: 6614-8 (2008) Article DOI: 10.1021/jm800865a BindingDB Entry DOI: 10.7270/Q261117R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of binding of [3H]-glycine to NMDA receptor | J Med Chem 37: 878-84 (1994) BindingDB Entry DOI: 10.7270/Q2X0662N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 2 (Homo sapiens (Human)) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Binding affinity for Excitatory amino acid transporter 2 (EAAT-2) in Glu uptake system | J Med Chem 45: 19-31 (2001) BindingDB Entry DOI: 10.7270/Q2KH0MMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 1 (Rattus norvegicus (Rat)) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 5.30E+4 | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Agonist activity at rat recombinant GluA1 receptor flip isoform expressed in HEK293 cells assessed as effect on cyclothiazide-induced calcium flux by... | Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, AMPA 2 (Rattus norvegicus) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 6.70E+4 | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Agonist activity at rat recombinant GluA2 receptor flip isoform expressed in HEK293 cells assessed as effect on cyclothiazide-induced calcium flux by... | Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GRIA3 (RAT) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.70E+4 | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Agonist activity at rat recombinant GluA3 receptor flip isoform expressed in HEK293 cells assessed as effect on cyclothiazide-induced calcium flux by... | Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, AMPA 4 (Rattus norvegicus) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Agonist activity at rat recombinant GluA4 receptor flip isoform expressed in HEK293 cells assessed as effect on cyclothiazide-induced calcium flux by... | Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GRIA3 (RAT) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Effective concentration of compound was determined for electrophysiological properties on Ionotropic glutamate receptor AMPA 3 (GluR3) using rat cort... | J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GRIA3 (RAT) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Agonist activity at rat recombinant GluA3 receptor flop isoform expressed in Xenopus oocytes | Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, AMPA (Mus musculus) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 8.70E+3 | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Effective concentration of compound was determined for electrophysiological properties on Metabotropic glutamate receptor 1 using rat cortical slice ... | J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 1 (Homo sapiens (Human)) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Binding affinity for Excitatory amino acid transporter 1 (EAAT-1) in Glu uptake system | J Med Chem 45: 19-31 (2001) BindingDB Entry DOI: 10.7270/Q2KH0MMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate (Rattus norvegicus) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Binding affinity of compound was determined against KA receptor, using radioligand [3H]- KA | J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Excitatory amino acid transporter 3 (Homo sapiens (Human)) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Binding affinity for Excitatory amino acid transporter 3 (EAAT-3) in Glu uptake system | J Med Chem 45: 19-31 (2001) BindingDB Entry DOI: 10.7270/Q2KH0MMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 1 (Rattus norvegicus (Rat)) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Binding affinity of compound was determined against Ionotropic glutamate receptor AMPA receptor, using radioligand [3H]- AMPA | J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 1 (Rattus norvegicus (Rat)) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 8.70E+3 | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Agonist activity at rat recombinant GluA1 receptor flop isoform expressed in Xenopus oocytes | Bioorg Med Chem 18: 1381-7 (2010) Article DOI: 10.1016/j.bmc.2009.12.072 BindingDB Entry DOI: 10.7270/Q27W6CB2 | |||||||||||
More data for this Ligand-Target Pair |