BDBM50002467 TMPNPNPthymidine 5'-[alpha,beta:beta,alpha-diimido]triphosphate

SMILES: Cc1cn([C@H]2C[C@@H](O)[C@@H](OP([O-])(=O)NP([O-])(=O)NP([O-])([O-])=O)O2)c(=O)[nH]c1=O

InChI Key: InChIKey=SNDXDQMCPTZXCJ-ATRFCDNQSA-J

Data: 1 KI

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50002467   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50002467 (TMPNPNPthymidine 5'-[alpha,beta:beta,alpha-diimido...) Show SMILES Cc1cn([C@H]2C[C@@H](O)[C@@H](OP([O-])(=O)NP([O-])(=O)NP([O-])([O-])=O)O2)c(=O)[nH]c1=O Show InChI InChI=1S/C9H17N4O12P3/c1-4-3-13(9(16)10-7(4)15)6-2-5(14)8(24-6)25-28(22,23)12-26(17,18)11-27(19,20)21/h3,5-6,8,14H,2H2,1H3,(H,10,15,16)(H6,11,12,17,18,19,20,21,22,23)/p-4/t5-,6-,8-/m1/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	PubMed	1.91E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description The compound was tested for the inhibition of human immunodeficiency virus-1 reverse transcriptase(HIV-1 RT).				J Med Chem 35: 1938-41 (1992) BindingDB Entry DOI: 10.7270/Q25B0336
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