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SMILES: COCCOc1cc2ncnc(NC3=CC(=O)C=C(OC)C3=O)c2cc1OC

InChI Key: InChIKey=PZNQXDDERNAPJZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50002588   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50002588
PNG
(CHEMBL2113183)
Show SMILES COCCOc1cc2ncnc(NC3=CC(=O)C=C(OC)C3=O)c2cc1OC |t:13,17|
Show InChI InChI=1S/C19H19N3O6/c1-25-4-5-28-16-9-13-12(8-15(16)26-2)19(21-10-20-13)22-14-6-11(23)7-17(27-3)18(14)24/h6-10H,4-5H2,1-3H3,(H,20,21,22)
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MMDB

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KEGG

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Similars
Article
PubMed
n/an/a 3.80n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of poly(Glu4-Tyr)peptide phosphorylation by recombinant VEGFR2 at 10 uM ATP

J Med Chem 48: 7560-81 (2005)


Article DOI: 10.1021/jm050559f
BindingDB Entry DOI: 10.7270/Q2028R3S
More data for this
Ligand-Target Pair