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BDBM50002643 4-(2-Chloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-(tetrahydro-furan-2-ylmethyl) ester 5-(1,1,3-trioxo-1,3-dihydro-1lambda*6*-benzo[d]isothiazol-2-ylmethyl) ester::CHEMBL79740

SMILES: CC1=NC(C)=C(C(C1C(=O)OCC1CCCO1)c1ccccc1Cl)C(=O)OCN1C(=O)c2ccccc2S1(=O)=O

InChI Key: InChIKey=UTRMTOGMXUZLQB-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50002643   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated L-type calcium channel alpha-1C subunit


(Oryctolagus cuniculus)
BDBM50002643
PNG
(4-(2-Chloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyrid...)
Show SMILES CC1=NC(C)=C(C(C1C(=O)OCC1CCCO1)c1ccccc1Cl)C(=O)OCN1C(=O)c2ccccc2S1(=O)=O |c:4,t:1|
Show InChI InChI=1S/C28H27ClN2O8S/c1-16-23(27(33)38-14-18-8-7-13-37-18)25(19-9-3-5-11-21(19)29)24(17(2)30-16)28(34)39-15-31-26(32)20-10-4-6-12-22(20)40(31,35)36/h3-6,9-12,18,23,25H,7-8,13-15H2,1-2H3
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PC cid
PC sid
UniChem
PubMed
n/an/a 10n/an/an/an/an/an/a



Alter, S.A.

Curated by ChEMBL


Assay Description
Blockade of calcium-evoked contractions in depolarized aortic strips


J Med Chem 35: 2407-14 (1992)


BindingDB Entry DOI: 10.7270/Q2BV7H7B
More data for this
Ligand-Target Pair