BDBM50002772 11-[2-(2-Hydroxy-benzoylamino)-ethylsulfanyl]-6,11-dihydro-dibenzo[b,e]oxepine-2-carboxylic acid::CHEMBL324256

SMILES: OC(=O)c1ccc2OCc3ccccc3C(SCCNC(=O)c3ccccc3O)c2c1

InChI Key: InChIKey=RQWKDIZMDQZESJ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50002772   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50002772 (11-[2-(2-Hydroxy-benzoylamino)-ethylsulfanyl]-6,11...) Show SMILES OC(=O)c1ccc2OCc3ccccc3C(SCCNC(=O)c3ccccc3O)c2c1 Show InChI InChI=1S/C24H21NO5S/c26-20-8-4-3-7-18(20)23(27)25-11-12-31-22-17-6-2-1-5-16(17)14-30-21-10-9-15(24(28)29)13-19(21)22/h1-10,13,22,26H,11-12,14H2,(H,25,27)(H,28,29)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of the thromboxane A2 receptor assayed by binding to guinea pig platelets using [3H]-U-46,619 as radioligand				J Med Chem 35: 3394-402 (1992) BindingDB Entry DOI: 10.7270/Q2NS0SV5
					More data for this Ligand-Target Pair
Prostanoid TP receptor (Homo sapiens (Human))	BDBM50002772 (11-[2-(2-Hydroxy-benzoylamino)-ethylsulfanyl]-6,11...) Show SMILES OC(=O)c1ccc2OCc3ccccc3C(SCCNC(=O)c3ccccc3O)c2c1 Show InChI InChI=1S/C24H21NO5S/c26-20-8-4-3-7-18(20)23(27)25-11-12-31-22-17-6-2-1-5-16(17)14-30-21-10-9-15(24(28)29)13-19(21)22/h1-10,13,22,26H,11-12,14H2,(H,25,27)(H,28,29)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Company, Ltd. Curated by ChEMBL					Assay Description Binding affinity at TXA2 receptor by measuring its ability to displace [3H]-U-46,619 from guinea pig platelets				J Med Chem 35: 3394-402 (1992) BindingDB Entry DOI: 10.7270/Q2NS0SV5
					More data for this Ligand-Target Pair