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BDBM50002820 11-[2-(2-Hydroxy-benzoimidazol-1-yl)-ethylidene]-6,11-dihydro-dibenzo[b,e]oxepine-2-carboxylic acid::CHEMBL114034

SMILES: OC(=O)c1ccc2OCc3ccccc3\C(=C/Cn3c4ccccc4[nH]c3=O)c2c1

InChI Key: InChIKey=CRUUOXDOAAENSX-WOJGMQOQSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50002820   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostanoid TP receptor


(Homo sapiens (Human))		BDBM50002820
PNG
(11-[2-(2-Hydroxy-benzoimidazol-1-yl)-ethylidene]-6...)
Show SMILES OC(=O)c1ccc2OCc3ccccc3\C(=C/Cn3c4ccccc4[nH]c3=O)c2c1
Show InChI InChI=1S/C24H18N2O4/c27-23(28)15-9-10-22-19(13-15)18(17-6-2-1-5-16(17)14-30-22)11-12-26-21-8-4-3-7-20(21)25-24(26)29/h1-11,13H,12,14H2,(H,25,29)(H,27,28)/b18-11+
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PubMed
 4n/an/an/an/an/an/an/an/a



Kyowa Hakko Kogyo Company, Ltd.

Curated by ChEMBL


Assay Description
Binding affinity at TXA2/PGH2 receptor by measuring its ability to displace [3H]-U-46,619 from guinea pig platelets

J Med Chem 35: 3402-13 (1992)


BindingDB Entry DOI: 10.7270/Q2J38RG1
More data for this
Ligand-Target Pair