BDBM50002830 (2R,3R,4R,5S)-2,5-Bis-(3,4-dimethoxy-phenyl)-3,4-dimethyl-tetrahydro-furan::(2S,3R,4R,5R)-2,5-Bis-(3,4-dimethoxy-phenyl)-3,4-dimethyl-tetrahydro-furan::CHEMBL112481
SMILES: COc1ccc(cc1OC)[C@H]1O[C@H]([C@H](C)[C@H]1C)c1ccc(OC)c(OC)c1
InChI Key: InChIKey=JLJAVUZBHSLLJL-SRLQQUAWSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Platelet activating factor receptor (Homo sapiens (Human)) | BDBM50002830 ((2R,3R,4R,5S)-2,5-Bis-(3,4-dimethoxy-phenyl)-3,4-d...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of the binding of [3H]C18-Platelet activating factor to human platelet membrane preparation | J Med Chem 35: 3474-82 (1992) BindingDB Entry DOI: 10.7270/Q2445N3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet activating factor receptor (Cavia porcellus) | BDBM50002830 ((2R,3R,4R,5S)-2,5-Bis-(3,4-dimethoxy-phenyl)-3,4-d...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory concentration required to inhibit PAF binding to rabbit platelet membrane | Bioorg Med Chem Lett 1: 327-332 (1991) Article DOI: 10.1016/S0960-894X(01)80818-0 BindingDB Entry DOI: 10.7270/Q2TM7BKP | |||||||||||
More data for this Ligand-Target Pair |