BDBM50002905 CHEMBL373535

SMILES: CC(Oc1ccccc1-c1cccnc1)C1=NCCN1

InChI Key: InChIKey=AFWQDDUMQAQVSC-UHFFFAOYSA-N

Data: 6 KI  8 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50002905   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adrenergic receptor (Homo sapiens (Human))	BDBM50002905 (CHEMBL373535) Show SMILES CC(Oc1ccccc1-c1cccnc1)C1=NCCN1 |t:17| Show InChI InChI=1S/C16H17N3O/c1-12(16-18-9-10-19-16)20-15-7-3-2-6-14(15)13-5-4-8-17-11-13/h2-8,11-12H,9-10H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from human adrenergic Alpha-2C receptor expressed in CHO cells				J Med Chem 47: 6160-73 (2004) Article DOI: 10.1021/jm0408215 BindingDB Entry DOI: 10.7270/Q2B27Z13
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50002905 (CHEMBL373535) Show SMILES CC(Oc1ccccc1-c1cccnc1)C1=NCCN1 |t:17| Show InChI InChI=1S/C16H17N3O/c1-12(16-18-9-10-19-16)20-15-7-3-2-6-14(15)13-5-4-8-17-11-13/h2-8,11-12H,9-10H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]RX 821002 from human adrenergic Alpha-2C receptor expressed in CHO cells				J Med Chem 50: 3964-8 (2007) Checked by Author Article DOI: 10.1021/jm061487a BindingDB Entry DOI: 10.7270/Q2W095NP
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50002905 (CHEMBL373535) Show SMILES CC(Oc1ccccc1-c1cccnc1)C1=NCCN1 |t:17| Show InChI InChI=1S/C16H17N3O/c1-12(16-18-9-10-19-16)20-15-7-3-2-6-14(15)13-5-4-8-17-11-13/h2-8,11-12H,9-10H2,1H3,(H,18,19)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	138	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from human adrenergic alpha2A receptor expressed in CHO cells				J Med Chem 47: 6160-73 (2004) Article DOI: 10.1021/jm0408215 BindingDB Entry DOI: 10.7270/Q2B27Z13
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50002905 (CHEMBL373535) Show SMILES CC(Oc1ccccc1-c1cccnc1)C1=NCCN1 |t:17| Show InChI InChI=1S/C16H17N3O/c1-12(16-18-9-10-19-16)20-15-7-3-2-6-14(15)13-5-4-8-17-11-13/h2-8,11-12H,9-10H2,1H3,(H,18,19)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	138	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]RX 821002 from human adrenergic alpha2A receptor expressed in CHO cells				J Med Chem 50: 3964-8 (2007) Checked by Author Article DOI: 10.1021/jm061487a BindingDB Entry DOI: 10.7270/Q2W095NP
					More data for this Ligand-Target Pair
Adrenergic receptor (Homo sapiens (Human))	BDBM50002905 (CHEMBL373535) Show SMILES CC(Oc1ccccc1-c1cccnc1)C1=NCCN1 |t:17| Show InChI InChI=1S/C16H17N3O/c1-12(16-18-9-10-19-16)20-15-7-3-2-6-14(15)13-5-4-8-17-11-13/h2-8,11-12H,9-10H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	933	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from human adrenergic alpha-2B receptor expressed in CHO cells				J Med Chem 47: 6160-73 (2004) Article DOI: 10.1021/jm0408215 BindingDB Entry DOI: 10.7270/Q2B27Z13
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50002905 (CHEMBL373535) Show SMILES CC(Oc1ccccc1-c1cccnc1)C1=NCCN1 |t:17| Show InChI InChI=1S/C16H17N3O/c1-12(16-18-9-10-19-16)20-15-7-3-2-6-14(15)13-5-4-8-17-11-13/h2-8,11-12H,9-10H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	933	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]RX 821002 from human adrenergic alpha-2B receptor expressed in CHO cells				J Med Chem 50: 3964-8 (2007) Checked by Author Article DOI: 10.1021/jm061487a BindingDB Entry DOI: 10.7270/Q2W095NP
					More data for this Ligand-Target Pair
Adrenergic receptor (Homo sapiens (Human))	BDBM50002905 (CHEMBL373535) Show SMILES CC(Oc1ccccc1-c1cccnc1)C1=NCCN1 |t:17| Show InChI InChI=1S/C16H17N3O/c1-12(16-18-9-10-19-16)20-15-7-3-2-6-14(15)13-5-4-8-17-11-13/h2-8,11-12H,9-10H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
Universit£ degli Studi di Camerino Curated by ChEMBL					Assay Description Agonist activity at human adrenergic Alpha-2C receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation				J Med Chem 47: 6160-73 (2004) Article DOI: 10.1021/jm0408215 BindingDB Entry DOI: 10.7270/Q2B27Z13
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50002905 (CHEMBL373535) Show SMILES CC(Oc1ccccc1-c1cccnc1)C1=NCCN1 |t:17| Show InChI InChI=1S/C16H17N3O/c1-12(16-18-9-10-19-16)20-15-7-3-2-6-14(15)13-5-4-8-17-11-13/h2-8,11-12H,9-10H2,1H3,(H,18,19)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	316	n/a	n/a	n/a	n/a
Universit£ degli Studi di Camerino Curated by ChEMBL					Assay Description Agonist activity at human adrenergic alpha-2A receptor expressed in CHO cells assessed as extracellular acidification by cytosensor microphysiometry				J Med Chem 47: 6160-73 (2004) Article DOI: 10.1021/jm0408215 BindingDB Entry DOI: 10.7270/Q2B27Z13
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50002905 (CHEMBL373535) Show SMILES CC(Oc1ccccc1-c1cccnc1)C1=NCCN1 |t:17| Show InChI InChI=1S/C16H17N3O/c1-12(16-18-9-10-19-16)20-15-7-3-2-6-14(15)13-5-4-8-17-11-13/h2-8,11-12H,9-10H2,1H3,(H,18,19)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	589	n/a	n/a	n/a	n/a
Universit£ degli Studi di Camerino Curated by ChEMBL					Assay Description Agonist activity at human adrenergic alpha-2A receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation				J Med Chem 47: 6160-73 (2004) Article DOI: 10.1021/jm0408215 BindingDB Entry DOI: 10.7270/Q2B27Z13
					More data for this Ligand-Target Pair
Adrenergic receptor (Homo sapiens (Human))	BDBM50002905 (CHEMBL373535) Show SMILES CC(Oc1ccccc1-c1cccnc1)C1=NCCN1 |t:17| Show InChI InChI=1S/C16H17N3O/c1-12(16-18-9-10-19-16)20-15-7-3-2-6-14(15)13-5-4-8-17-11-13/h2-8,11-12H,9-10H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Universit£ degli Studi di Camerino Curated by ChEMBL					Assay Description Agonist activity at human adrenergic alpha-2B receptor expressed in CHO cells assessed as extracellular acidification by cytosensor microphysiometry				J Med Chem 47: 6160-73 (2004) Article DOI: 10.1021/jm0408215 BindingDB Entry DOI: 10.7270/Q2B27Z13
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50002905 (CHEMBL373535) Show SMILES CC(Oc1ccccc1-c1cccnc1)C1=NCCN1 |t:17| Show InChI InChI=1S/C16H17N3O/c1-12(16-18-9-10-19-16)20-15-7-3-2-6-14(15)13-5-4-8-17-11-13/h2-8,11-12H,9-10H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
Università degli Studi di Camerino Curated by ChEMBL					Assay Description Agonistic potency at human adrenergic alpha2C receptor expressed in CHO cells assessed as forskolin-induced cAMP accumulation				J Med Chem 50: 3964-8 (2007) Checked by Author Article DOI: 10.1021/jm061487a BindingDB Entry DOI: 10.7270/Q2W095NP
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50002905 (CHEMBL373535) Show SMILES CC(Oc1ccccc1-c1cccnc1)C1=NCCN1 |t:17| Show InChI InChI=1S/C16H17N3O/c1-12(16-18-9-10-19-16)20-15-7-3-2-6-14(15)13-5-4-8-17-11-13/h2-8,11-12H,9-10H2,1H3,(H,18,19)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	316	n/a	n/a	n/a	n/a
Università degli Studi di Camerino Curated by ChEMBL					Assay Description Agonistic potency at human adrenergic alpha-2A receptor expressed in CHO cells assessed as forskolin-induced cAMP accumulation				J Med Chem 50: 3964-8 (2007) Checked by Author Article DOI: 10.1021/jm061487a BindingDB Entry DOI: 10.7270/Q2W095NP
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50002905 (CHEMBL373535) Show SMILES CC(Oc1ccccc1-c1cccnc1)C1=NCCN1 |t:17| Show InChI InChI=1S/C16H17N3O/c1-12(16-18-9-10-19-16)20-15-7-3-2-6-14(15)13-5-4-8-17-11-13/h2-8,11-12H,9-10H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Università degli Studi di Camerino Curated by ChEMBL					Assay Description Agonistic potency at human adrenergic alpha-2B receptor expressed in CHO cells assessed as forskolin-induced cAMP accumulation				J Med Chem 50: 3964-8 (2007) Checked by Author Article DOI: 10.1021/jm061487a BindingDB Entry DOI: 10.7270/Q2W095NP
					More data for this Ligand-Target Pair
Adrenergic receptor (Homo sapiens (Human))	BDBM50002905 (CHEMBL373535) Show SMILES CC(Oc1ccccc1-c1cccnc1)C1=NCCN1 |t:17| Show InChI InChI=1S/C16H17N3O/c1-12(16-18-9-10-19-16)20-15-7-3-2-6-14(15)13-5-4-8-17-11-13/h2-8,11-12H,9-10H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
Universit£ degli Studi di Camerino Curated by ChEMBL					Assay Description Agonist activity at human adrenergic alpha-2C receptor expressed in CHO cells assessed as extracellular acidification by cytosensor microphysiometry				J Med Chem 47: 6160-73 (2004) Article DOI: 10.1021/jm0408215 BindingDB Entry DOI: 10.7270/Q2B27Z13
					More data for this Ligand-Target Pair