BDBM50003247 4-(4-Morpholin-4-ylmethyl-benzoyl)-thiophene-2-sulfonic acid amide; hydrochloride::CHEMBL545756

SMILES: NS(=O)(=O)c1cc(cs1)C(=O)c1ccc(CN2CCOCC2)cc1

InChI Key: InChIKey=MYCKFSFRWHNCDM-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003247   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50003247 (4-(4-Morpholin-4-ylmethyl-benzoyl)-thiophene-2-sul...) Show SMILES NS(=O)(=O)c1cc(cs1)C(=O)c1ccc(CN2CCOCC2)cc1 Show InChI InChI=1S/C16H18N2O4S2/c17-24(20,21)15-9-14(11-23-15)16(19)13-3-1-12(2-4-13)10-18-5-7-22-8-6-18/h1-4,9,11H,5-8,10H2,(H2,17,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Compound was tested in vitro for binding affinity against human carbonic anhydrase II; (ki*10e-9)				J Med Chem 35: 3822-31 (1992) BindingDB Entry DOI: 10.7270/Q2ZG6SV4
					More data for this Ligand-Target Pair