BDBM50003394 2-Methyl-4-{1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-yl]-ethoxy}-quinoline::CHEMBL341223
SMILES: CC(Oc1cc(C)nc2ccccc12)c1ccc(cc1)-c1ccccc1-c1nnn[nH]1
InChI Key: InChIKey=GSBQRUQGRWSSFO-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Type-1 angiotensin II receptor (Cavia porcellus) | BDBM50003394 (2-Methyl-4-{1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-yl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition of the specific binding of [125I]-angiotensin II to a guinea pig adrenal membrane preparation | J Med Chem 35: 4027-38 (1992) BindingDB Entry DOI: 10.7270/Q2G44P8Q | |||||||||||
More data for this Ligand-Target Pair |