BDBM50003426 1-(4-Fluoro-phenyl)-3-(hydroxy-phenethyl-amino)-propenone::CHEMBL130726

SMILES: ON(CCc1ccccc1)\C=C/C(=O)c1ccc(F)cc1

InChI Key: InChIKey=KIAVJOXMWVVZJL-QBFSEMIESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003426   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50003426 (1-(4-Fluoro-phenyl)-3-(hydroxy-phenethyl-amino)-pr...) Show SMILES ON(CCc1ccccc1)\C=C/C(=O)c1ccc(F)cc1 Show InChI InChI=1S/C17H16FNO2/c18-16-8-6-15(7-9-16)17(20)11-13-19(21)12-10-14-4-2-1-3-5-14/h1-9,11,13,21H,10,12H2/b13-11-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cell line.				J Med Chem 35: 4061-8 (1992) BindingDB Entry DOI: 10.7270/Q2BC3XHJ
					More data for this Ligand-Target Pair