BDBM50003438 1-(3,5-Bis-trifluoromethyl-phenyl)-3-(hydroxy-methyl-amino)-propenone::CHEMBL340652

SMILES: CN(O)\C=C/C(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=WGHXKDXVLZYAHS-IHWYPQMZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003438   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50003438 (1-(3,5-Bis-trifluoromethyl-phenyl)-3-(hydroxy-meth...) Show SMILES CN(O)\C=C/C(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C12H9F6NO2/c1-19(21)3-2-10(20)7-4-8(11(13,14)15)6-9(5-7)12(16,17)18/h2-6,21H,1H3/b3-2-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	910	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cell line.				J Med Chem 35: 4061-8 (1992) BindingDB Entry DOI: 10.7270/Q2BC3XHJ
					More data for this Ligand-Target Pair