BDBM50003447 (Z)-3-(Cyclohexyl-hydroxy-amino)-1-(4-fluoro-phenyl)-propenone::3-(Cyclohexyl-hydroxy-amino)-1-(4-fluoro-phenyl)-propenone::CHEMBL274373

SMILES: ON(\C=C/C(=O)c1ccc(F)cc1)C1CCCCC1

InChI Key: InChIKey=ZHWUMBJLOKAFHW-KHPPLWFESA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50003447   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50003447 ((Z)-3-(Cyclohexyl-hydroxy-amino)-1-(4-fluoro-pheny...) Show SMILES ON(\C=C/C(=O)c1ccc(F)cc1)C1CCCCC1 Show InChI InChI=1S/C15H18FNO2/c16-13-8-6-12(7-9-13)15(18)10-11-17(19)14-4-2-1-3-5-14/h6-11,14,19H,1-5H2/b11-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cell line.				J Med Chem 35: 4061-8 (1992) BindingDB Entry DOI: 10.7270/Q2BC3XHJ
					More data for this Ligand-Target Pair
Cyclooxygenase (Bos taurus)	BDBM50003447 ((Z)-3-(Cyclohexyl-hydroxy-amino)-1-(4-fluoro-pheny...) Show SMILES ON(\C=C/C(=O)c1ccc(F)cc1)C1CCCCC1 Show InChI InChI=1S/C15H18FNO2/c16-13-8-6-12(7-9-13)15(18)10-11-17(19)14-4-2-1-3-5-14/h6-11,14,19H,1-5H2/b11-10-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>7.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for inhibition against cyclooxygenase of bovine seminal vesicles				Bioorg Med Chem Lett 2: 1079-1084 (1992) Article DOI: 10.1016/S0960-894X(00)80622-8 BindingDB Entry DOI: 10.7270/Q2S75G70
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50003447 ((Z)-3-(Cyclohexyl-hydroxy-amino)-1-(4-fluoro-pheny...) Show SMILES ON(\C=C/C(=O)c1ccc(F)cc1)C1CCCCC1 Show InChI InChI=1S/C15H18FNO2/c16-13-8-6-12(7-9-13)15(18)10-11-17(19)14-4-2-1-3-5-14/h6-11,14,19H,1-5H2/b11-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of 5-Lipoxygenase of rat basophilic leukemia cells				Bioorg Med Chem Lett 2: 1079-1084 (1992) Article DOI: 10.1016/S0960-894X(00)80622-8 BindingDB Entry DOI: 10.7270/Q2S75G70
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50003447 ((Z)-3-(Cyclohexyl-hydroxy-amino)-1-(4-fluoro-pheny...) Show SMILES ON(\C=C/C(=O)c1ccc(F)cc1)C1CCCCC1 Show InChI InChI=1S/C15H18FNO2/c16-13-8-6-12(7-9-13)15(18)10-11-17(19)14-4-2-1-3-5-14/h6-11,14,19H,1-5H2/b11-10-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for inhibition against Phospholipase A2 of Croatalus adamanteus				Bioorg Med Chem Lett 2: 1079-1084 (1992) Article DOI: 10.1016/S0960-894X(00)80622-8 BindingDB Entry DOI: 10.7270/Q2S75G70
					More data for this Ligand-Target Pair