BDBM50003451 (Z)-1-Biphenyl-4-yl-3-(hydroxy-methyl-amino)-propenone::1-Biphenyl-4-yl-3-(hydroxy-methyl-amino)-propenone::CHEMBL274187

SMILES: CN(O)\C=C/C(=O)c1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=ZZYCZRUJXOZHRM-QXMHVHEDSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50003451   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50003451 ((Z)-1-Biphenyl-4-yl-3-(hydroxy-methyl-amino)-prope...) Show SMILES CN(O)\C=C/C(=O)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C16H15NO2/c1-17(19)12-11-16(18)15-9-7-14(8-10-15)13-5-3-2-4-6-13/h2-12,19H,1H3/b12-11-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of 5-Lipoxygenase of rat basophilic leukemia cells				Bioorg Med Chem Lett 2: 1079-1084 (1992) Article DOI: 10.1016/S0960-894X(00)80622-8 BindingDB Entry DOI: 10.7270/Q2S75G70
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50003451 ((Z)-1-Biphenyl-4-yl-3-(hydroxy-methyl-amino)-prope...) Show SMILES CN(O)\C=C/C(=O)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C16H15NO2/c1-17(19)12-11-16(18)15-9-7-14(8-10-15)13-5-3-2-4-6-13/h2-12,19H,1H3/b12-11-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cell line.				J Med Chem 35: 4061-8 (1992) BindingDB Entry DOI: 10.7270/Q2BC3XHJ
					More data for this Ligand-Target Pair