BDBM50003458 (Z)-3-(Benzyl-hydroxy-amino)-1-(4-fluoro-phenyl)-but-2-en-1-one::3-(Benzyl-hydroxy-amino)-1-(4-fluoro-phenyl)-but-2-en-1-one::CHEMBL11871
SMILES: CC(=CC(=O)c1ccc(F)cc1)N(O)Cc1ccccc1
InChI Key: InChIKey=JPSKTAJUFHZZII-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50003458 ((Z)-3-(Benzyl-hydroxy-amino)-1-(4-fluoro-phenyl)-b...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of 5-Lipoxygenase of rat basophilic leukemia cells | Bioorg Med Chem Lett 2: 1079-1084 (1992) Article DOI: 10.1016/S0960-894X(00)80622-8 BindingDB Entry DOI: 10.7270/Q2S75G70 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50003458 ((Z)-3-(Benzyl-hydroxy-amino)-1-(4-fluoro-phenyl)-b...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cell line. | J Med Chem 35: 4061-8 (1992) BindingDB Entry DOI: 10.7270/Q2BC3XHJ | |||||||||||
More data for this Ligand-Target Pair |