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SMILES: Clc1ccc2c(NCCNC(=S)Nc3ccccc3Cl)ccnc2c1

InChI Key: InChIKey=RQSSBSNGEYFOOB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003656   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histidine-rich protein PFHRP-II


(Plasmodium falciparum)		BDBM50003656
PNG
(CHEMBL452640)
Show SMILES Clc1ccc2c(NCCNC(=S)Nc3ccccc3Cl)ccnc2c1
Show InChI InChI=1S/C18H16Cl2N4S/c19-12-5-6-13-15(7-8-21-17(13)11-12)22-9-10-23-18(25)24-16-4-2-1-3-14(16)20/h1-8,11H,9-10H2,(H,21,22)(H2,23,24,25)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 5.60n/an/an/an/an/an/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Antiplasmodial activity as inhibition of beta-hematin against Plasmodium yoelii N67 infected Swiss mice (Mus musculus) erythrocytes

Bioorg Med Chem Lett 19: 2570-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.026
BindingDB Entry DOI: 10.7270/Q2JD4Z8D
More data for this
Ligand-Target Pair