BDBM50003657 CHEMBL466905

SMILES: Clc1ccc2c(NCCCNC(=S)Nc3ccccc3)ccnc2c1

InChI Key: InChIKey=PSMMGWRJWWQETD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003657   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histidine-rich protein (Plasmodium falciparum)	BDBM50003657 (CHEMBL466905) Show SMILES Clc1ccc2c(NCCCNC(=S)Nc3ccccc3)ccnc2c1 Show InChI InChI=1S/C19H19ClN4S/c20-14-7-8-16-17(9-12-22-18(16)13-14)21-10-4-11-23-19(25)24-15-5-2-1-3-6-15/h1-3,5-9,12-13H,4,10-11H2,(H,21,22)(H2,23,24,25)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Antiplasmodial activity as inhibition of beta-hematin against Plasmodium yoelii N67 infected Swiss mice (Mus musculus) erythrocytes				Bioorg Med Chem Lett 19: 2570-3 (2009) Article DOI: 10.1016/j.bmcl.2009.03.026 BindingDB Entry DOI: 10.7270/Q2JD4Z8D
					More data for this Ligand-Target Pair