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SMILES: CCCC\N=C1/SC(=O)C(=O)N1CCNc1ccnc2cc(Cl)ccc12

InChI Key: InChIKey=FPDFBYMCESTWOG-PYCFMQQDSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003672   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histidine-rich protein PFHRP-II


(Plasmodium falciparum)		BDBM50003672
PNG
(CHEMBL512078)
Show SMILES CCCC\N=C1/SC(=O)C(=O)N1CCNc1ccnc2cc(Cl)ccc12
Show InChI InChI=1S/C18H19ClN4O2S/c1-2-3-7-22-18-23(16(24)17(25)26-18)10-9-21-14-6-8-20-15-11-12(19)4-5-13(14)15/h4-6,8,11H,2-3,7,9-10H2,1H3,(H,20,21)/b22-18-
UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.44E+4n/an/an/an/an/an/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Antiplasmodial activity as inhibition of beta-hematin against Plasmodium yoelii N67 infected Swiss mice (Mus musculus) erythrocytes

Bioorg Med Chem Lett 19: 2570-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.026
BindingDB Entry DOI: 10.7270/Q2JD4Z8D
More data for this
Ligand-Target Pair