null
SMILES: Clc1ccc2c(NCCN3C(=O)C(=O)S\C3=N/CC=C)ccnc2c1
InChI Key: InChIKey=XMIDWGYUCDPKCQ-FXBPSFAMSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histidine-rich protein PFHRP-II (Plasmodium falciparum) | BDBM50003673 (CHEMBL467521) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute Curated by ChEMBL | Assay Description Antiplasmodial activity as inhibition of beta-hematin against Plasmodium yoelii N67 infected Swiss mice (Mus musculus) erythrocytes | Bioorg Med Chem Lett 19: 2570-3 (2009) Article DOI: 10.1016/j.bmcl.2009.03.026 BindingDB Entry DOI: 10.7270/Q2JD4Z8D | |||||||||||
More data for this Ligand-Target Pair |