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SMILES: Clc1ccc2c(NCCCN3\C(SC(=O)C3=O)=N\c3ccccc3)ccnc2c1

InChI Key: InChIKey=APAFDMYDCGVCPT-DAFNUICNSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003676   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histidine-rich protein PFHRP-II


(Plasmodium falciparum)		BDBM50003676
PNG
(CHEMBL511925)
Show SMILES Clc1ccc2c(NCCCN3\C(SC(=O)C3=O)=N\c3ccccc3)ccnc2c1
Show InChI InChI=1S/C21H17ClN4O2S/c22-14-7-8-16-17(9-11-24-18(16)13-14)23-10-4-12-26-19(27)20(28)29-21(26)25-15-5-2-1-3-6-15/h1-3,5-9,11,13H,4,10,12H2,(H,23,24)/b25-21-
UniProtKB/SwissProt

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UniChem

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Article
PubMed
n/an/a 8.40n/an/an/an/an/an/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Antiplasmodial activity as inhibition of beta-hematin against Plasmodium yoelii N67 infected Swiss mice (Mus musculus) erythrocytes

Bioorg Med Chem Lett 19: 2570-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.026
BindingDB Entry DOI: 10.7270/Q2JD4Z8D
More data for this
Ligand-Target Pair