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SMILES: Clc1ccc2c(NCCCN3C(=O)C(=O)N(CC=C)C3=S)ccnc2c1

InChI Key: InChIKey=DNDCWPQSJPKEIR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003687   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histidine-rich protein PFHRP-II


(Plasmodium falciparum)		BDBM50003687
PNG
(CHEMBL466027)
Show SMILES Clc1ccc2c(NCCCN3C(=O)C(=O)N(CC=C)C3=S)ccnc2c1
Show InChI InChI=1S/C18H17ClN4O2S/c1-2-9-22-16(24)17(25)23(18(22)26)10-3-7-20-14-6-8-21-15-11-12(19)4-5-13(14)15/h2,4-6,8,11H,1,3,7,9-10H2,(H,20,21)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 12n/an/an/an/an/an/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Antiplasmodial activity as inhibition of beta-hematin against Plasmodium yoelii N67 infected Swiss mice (Mus musculus) erythrocytes

Bioorg Med Chem Lett 19: 2570-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.026
BindingDB Entry DOI: 10.7270/Q2JD4Z8D
More data for this
Ligand-Target Pair