BDBM50003980 CHEMBL2180434

SMILES: Cc1ncccc1-c1cccc(c1)-c1nc(NCc2ccncc2)c2ccncc2n1

InChI Key: InChIKey=OFVWQEBJFHDRBR-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003980   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50003980 (CHEMBL2180434) Show SMILES Cc1ncccc1-c1cccc(c1)-c1nc(NCc2ccncc2)c2ccncc2n1 Show InChI InChI=1S/C25H20N6/c1-17-21(6-3-10-28-17)19-4-2-5-20(14-19)24-30-23-16-27-13-9-22(23)25(31-24)29-15-18-7-11-26-12-8-18/h2-14,16H,15H2,1H3,(H,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of PDE10A by fluorescence polarization assay				J Med Chem 55: 7299-331 (2012) Article DOI: 10.1021/jm3004976 BindingDB Entry DOI: 10.7270/Q2C24XJK
					More data for this Ligand-Target Pair