BDBM50004115 5-Cyclopropyl-1-ethoxymethyl-6-phenylsulfanyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one::CHEMBL335584

SMILES: CCOCn1c(Sc2ccccc2)c(C2CC2)c(=O)[nH]c1=S

InChI Key: InChIKey=USUVLNAUWPBOKC-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50004115   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50004115 (5-Cyclopropyl-1-ethoxymethyl-6-phenylsulfanyl-2-th...) Show SMILES CCOCn1c(Sc2ccccc2)c(C2CC2)c(=O)[nH]c1=S Show InChI InChI=1S/C16H18N2O2S2/c1-2-20-10-18-15(22-12-6-4-3-5-7-12)13(11-8-9-11)14(19)17-16(18)21/h3-7,11H,2,8-10H2,1H3,(H,17,19,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	95	n/a	n/a	n/a	n/a
Université d'Orléans Curated by ChEMBL					Assay Description Inhibitory concentration against HIV-1 reverse transcriptase				J Med Chem 40: 4257-64 (1998) Article DOI: 10.1021/jm970110p BindingDB Entry DOI: 10.7270/Q2WS8SC3
					More data for this Ligand-Target Pair