BDBM50004138 1-Benzyloxymethyl-6-(3,5-dimethyl-phenylsulfanyl)-5-ethyl-1H-pyrimidine-2,4-dione::CHEMBL291926

SMILES: CCc1c(Sc2cc(C)cc(C)c2)n(COCc2ccccc2)c(=O)[nH]c1=O

InChI Key: InChIKey=KYQAKOHJHCUILQ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50004138   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50004138 (1-Benzyloxymethyl-6-(3,5-dimethyl-phenylsulfanyl)-...) Show SMILES CCc1c(Sc2cc(C)cc(C)c2)n(COCc2ccccc2)c(=O)[nH]c1=O Show InChI InChI=1S/C22H24N2O3S/c1-4-19-20(25)23-22(26)24(14-27-13-17-8-6-5-7-9-17)21(19)28-18-11-15(2)10-16(3)12-18/h5-12H,4,13-14H2,1-3H3,(H,23,25,26)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.20	n/a	n/a	n/a	n/a
Université d'Orléans Curated by ChEMBL					Assay Description Inhibitory concentration against HIV-1 reverse transcriptase				J Med Chem 40: 4257-64 (1998) Article DOI: 10.1021/jm970110p BindingDB Entry DOI: 10.7270/Q2WS8SC3
					More data for this Ligand-Target Pair