BDBM50004142 1,5-Dimethyl-6-phenylsulfanyl-1H-pyrimidine-2,4-dione::CHEMBL290685
SMILES: Cc1c(Sc2ccccc2)n(C)c(=O)[nH]c1=O
InChI Key: InChIKey=HEAFEFDUVJFUPX-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1) | BDBM50004142 (1,5-Dimethyl-6-phenylsulfanyl-1H-pyrimidine-2,4-di...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | >1.50E+5 | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of HIV-1 reverse transcriptase at 37 degree centigrade | J Med Chem 44: 145-54 (2001) BindingDB Entry DOI: 10.7270/Q2VX0FRX | |||||||||||
More data for this Ligand-Target Pair |