BDBM50004337 (4-Fluoro-phenyl)-[1-(4-phenyl-butyl)-piperidin-4-yl]-methanone::(4-Fluoro-phenyl)-[1-(4-phenyl-butyl)-piperidin-4-yl]-methanone; hydrogen oxalate salt::CHEMBL1788135::CHEMBL19259

SMILES: Fc1ccc(cc1)C(=O)C1CCN(CCCCc2ccccc2)CC1

InChI Key: InChIKey=FTJXZACAQRDRNT-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50004337   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50004337 ((4-Fluoro-phenyl)-[1-(4-phenyl-butyl)-piperidin-4-...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCCCc2ccccc2)CC1 Show InChI InChI=1S/C22H26FNO/c23-21-11-9-19(10-12-21)22(25)20-13-16-24(17-14-20)15-5-4-8-18-6-2-1-3-7-18/h1-3,6-7,9-12,20H,4-5,8,13-17H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Curated by ChEMBL					Assay Description Binding affinity for human 5-hydroxytryptamine 2A receptor				J Med Chem 44: 477-501 (2001) BindingDB Entry DOI: 10.7270/Q24Q7VQH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50004337 ((4-Fluoro-phenyl)-[1-(4-phenyl-butyl)-piperidin-4-...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCCCc2ccccc2)CC1 Show InChI InChI=1S/C22H26FNO/c23-21-11-9-19(10-12-21)22(25)20-13-16-24(17-14-20)15-5-4-8-18-6-2-1-3-7-18/h1-3,6-7,9-12,20H,4-5,8,13-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2A receptor				J Med Chem 38: 1196-202 (1995) BindingDB Entry DOI: 10.7270/Q2CZ37TG
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50004337 ((4-Fluoro-phenyl)-[1-(4-phenyl-butyl)-piperidin-4-...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCCCc2ccccc2)CC1 Show InChI InChI=1S/C22H26FNO/c23-21-11-9-19(10-12-21)22(25)20-13-16-24(17-14-20)15-5-4-8-18-6-2-1-3-7-18/h1-3,6-7,9-12,20H,4-5,8,13-17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor in rat using [3H]ketanserin as radioligand				J Med Chem 35: 4903-10 (1993) BindingDB Entry DOI: 10.7270/Q26T0N86
					More data for this Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat))	BDBM50004337 ((4-Fluoro-phenyl)-[1-(4-phenyl-butyl)-piperidin-4-...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCCCc2ccccc2)CC1 Show InChI InChI=1S/C22H26FNO/c23-21-11-9-19(10-12-21)22(25)20-13-16-24(17-14-20)15-5-4-8-18-6-2-1-3-7-18/h1-3,6-7,9-12,20H,4-5,8,13-17H2	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	620	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand				J Med Chem 35: 4903-10 (1993) BindingDB Entry DOI: 10.7270/Q26T0N86
					More data for this Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat))	BDBM50004337 ((4-Fluoro-phenyl)-[1-(4-phenyl-butyl)-piperidin-4-...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCCCc2ccccc2)CC1 Show InChI InChI=1S/C22H26FNO/c23-21-11-9-19(10-12-21)22(25)20-13-16-24(17-14-20)15-5-4-8-18-6-2-1-3-7-18/h1-3,6-7,9-12,20H,4-5,8,13-17H2	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	620	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2C receptor				J Med Chem 38: 1196-202 (1995) BindingDB Entry DOI: 10.7270/Q2CZ37TG
					More data for this Ligand-Target Pair