BindingDB PrimarySearch

null

SMILES: C[N+](C)(C)CCOC(N)=O

InChI Key: InChIKey=VPJXQGSRWJZDOB-UHFFFAOYSA-O

PDB links: 4 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 277 hits for monomerid = 50004656
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
American Cyanamid Company Curated by ChEMBL					Assay Description Binding activity to the muscarinic acetylcholine receptor in rat cortex, assayed using [3H]CD as a radioligand.				J Med Chem 33: 3190-8 (1990) BindingDB Entry DOI: 10.7270/Q2M32Z0K
American Cyanamid Company Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Division of American Cyanamid Company Curated by ChEMBL					Assay Description Binding affinity at [3H]CD radiolabeled muscarinic M2 receptor in rat cortex.				J Med Chem 36: 3533-41 (1994) BindingDB Entry DOI: 10.7270/Q28916GB
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by PDSP K_i Database									Mol Pharmacol 64: 865-75 (2003) Article DOI: 10.1124/mol.64.4.865 BindingDB Entry DOI: 10.7270/Q2RX99PV
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Mus musculus)	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Carolina Curated by ChEMBL					Assay Description Ability of the compound to displace [3H]-oxotremorine ([3H]-OXO-M) from mouse cerebral cortex				J Med Chem 35: 3141-7 (1992) BindingDB Entry DOI: 10.7270/Q200012X
University of South Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Carolina Curated by ChEMBL					Assay Description Compound was evaluated for the binding affinity by displacing [3H]oxotremorine from mouse cerebral cortex tissue.				J Med Chem 35: 1102-8 (1992) BindingDB Entry DOI: 10.7270/Q28K79QR
University of South Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Carolina Curated by ChEMBL					Assay Description Compound was evaluated for the binding affinity by displacing [3H]oxotremorine from mouse cerebral cortex tissue.				J Med Chem 35: 1102-8 (1992) BindingDB Entry DOI: 10.7270/Q28K79QR
University of South Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Astra Arcus USA Curated by ChEMBL					Assay Description Binding affinity against Muscarinic acetylcholine receptor using [3H]-OXO-M as the radioligand.				J Med Chem 41: 4181-5 (1998) Article DOI: 10.1021/jm980192x BindingDB Entry DOI: 10.7270/Q2PV6P3B
Astra Arcus USA Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]- Oxo-M binding to muscarinic acetylcholine receptor of rat heart membrane preparation.				J Med Chem 35: 2184-91 (1992) BindingDB Entry DOI: 10.7270/Q2B27T74
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]OXO-M binding against muscarinic acetylcholine receptor in rat brain membranes				J Med Chem 34: 3164-71 (1991) BindingDB Entry DOI: 10.7270/Q2V988Q7
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Inhibition of [3H]- quinuclidinyl benzilate binding to human Muscarinic acetylcholine receptor M2 expressed in CHO cell membrane				J Med Chem 43: 2514-22 (2000) BindingDB Entry DOI: 10.7270/Q29W0DR6
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Inhibition of binding of [3H]quinuclidinyl benzilate to muscarinic receptors in membranes of CHO cells transfected with Muscarinic acetylcholine rece...				J Med Chem 41: 2047-55 (1998) Article DOI: 10.1021/jm9705115 BindingDB Entry DOI: 10.7270/Q2B27VZZ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Inhibition of binding of [3H]quinuclidinyl benzilate to Muscarinic acetylcholine receptor M2 in rat cerebral cortical membranes				J Med Chem 41: 2047-55 (1998) Article DOI: 10.1021/jm9705115 BindingDB Entry DOI: 10.7270/Q2B27VZZ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Mus musculus)	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Toledo Curated by ChEMBL					Assay Description Binding affinity (low) of [3H](R)-QNB binding to Muscarinic acetylcholine receptor M1 expressed in A9 L cell line in the absence of 300 uM GTP-gamma-...				J Med Chem 40: 1230-46 (1997) Article DOI: 10.1021/jm960467d BindingDB Entry DOI: 10.7270/Q28916HS
The University of Toledo Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Inhibition of [3H]- oxotremorine-M binding to human Muscarinic acetylcholine receptor M4 in CHO cell membranes				J Med Chem 43: 2514-22 (2000) BindingDB Entry DOI: 10.7270/Q29W0DR6
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Inhibition of [3H]- oxotremorine-M binding to human Muscarinic acetylcholine receptor M4 in CHO cell membranes				J Med Chem 43: 2514-22 (2000) BindingDB Entry DOI: 10.7270/Q29W0DR6
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by PDSP K_i Database									J Pharmacol Exp Ther 256: 689-94 (1991) BindingDB Entry DOI: 10.7270/Q25T3J06
University of Arizona Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Inhibition of binding of [3H]oxotremorine M to Muscarinic acetylcholine receptor M1 in rat cerebral cortical membranes				J Med Chem 41: 2047-55 (1998) Article DOI: 10.1021/jm9705115 BindingDB Entry DOI: 10.7270/Q2B27VZZ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Affinity versus [3H]oxotremorine M (agonist) binding to Muscarinic acetylcholine receptor M1 in Rat Cerebral Cortical Membranes, (Kd=0.75 nM)				J Med Chem 41: 2047-55 (1998) Article DOI: 10.1021/jm9705115 BindingDB Entry DOI: 10.7270/Q2B27VZZ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Mus musculus)	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Toledo Curated by ChEMBL					Assay Description Binding affinity of [3H](R)-QNB binding to Muscarinic acetylcholine receptor M1 expressed in A9 L cell line in the presence of 300 uM GTP-gamma-S				J Med Chem 40: 1230-46 (1997) Article DOI: 10.1021/jm960467d BindingDB Entry DOI: 10.7270/Q28916HS
The University of Toledo Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Inhibition of [3H]- oxotremorine-M binding to human Muscarinic acetylcholine receptor M2 expressed in CHO cell membranes				J Med Chem 43: 2514-22 (2000) BindingDB Entry DOI: 10.7270/Q29W0DR6
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	66.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Targacept, Inc. Curated by PDSP K_i Database									J Pharmacol Exp Ther 312: 619-26 (2005) Article DOI: 10.1124/jpet.104.075069 BindingDB Entry DOI: 10.7270/Q2BK19XS
Targacept, Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	PubMed	68.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP K_i Database									J Pharmacol Exp Ther 276: 289-97 (1996) BindingDB Entry DOI: 10.7270/Q2GM85T1
Abbott Laboratories Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor (RAT)	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	73	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse Curated by PDSP K_i Database									Mol Pharmacol 57: 642-9 (2000) Article DOI: 10.1124/mol.57.3.642 BindingDB Entry DOI: 10.7270/Q21C1VF8
					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor (RAT)	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. J. Reynolds Tobacco Company Curated by PDSP K_i Database									Mol Pharmacol 29: 448-54 (1986) BindingDB Entry DOI: 10.7270/Q269722Z
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Barrow Neurological Institute Curated by PDSP K_i Database									Mol Pharmacol 64: 1283-94 (2003) Article DOI: 10.1124/mol.64.6.1283 BindingDB Entry DOI: 10.7270/Q2GF0S2V
Barrow Neurological Institute Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Promotilin (RABBIT)	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	158	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Melbourne Curated by PDSP K_i Database									Clin Exp Pharmacol Physiol 26: 242-5 (1999) Article DOI: 10.1046/j.1440-1681.1999.03022.x BindingDB Entry DOI: 10.7270/Q2VX0F2Z
University of Melbourne Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Inhibition of [3H]- oxotremorine-M binding to human Muscarinic acetylcholine receptor M1 expressed in CHO cell membranes				J Med Chem 43: 2514-22 (2000) BindingDB Entry DOI: 10.7270/Q29W0DR6
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-2/beta-2 (Rattus norvegicus (Rat))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University School of Medicine Curated by ChEMBL					Assay Description Binding affinity towards rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in HEK293 cells using [3H]EB as radioligand				Bioorg Med Chem Lett 14: 1845-8 (2004) Article DOI: 10.1016/j.bmcl.2003.09.105 BindingDB Entry DOI: 10.7270/Q2TB17G2
Georgetown University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-2 (Rattus norvegicus (Rat))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Curated by PDSP K_i Database									J Pharmacol Exp Ther 310: 98-107 (2004) Article DOI: 10.1124/jpet.104.066787 BindingDB Entry DOI: 10.7270/Q2XG9PQX
Georgetown University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor (RAT)	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	PubMed	325	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by PDSP K_i Database									J Pharmacol Exp Ther 270: 159-66 (1994) BindingDB Entry DOI: 10.7270/Q22Z141C
University of California Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	PubMed	331	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by PDSP K_i Database									J Pharmacol Exp Ther 279: 1335-44 (1996) BindingDB Entry DOI: 10.7270/Q2XG9PPG
University of California Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor (RAT)	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	428	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Curated by PDSP K_i Database									Mol Pharmacol 54: 322-33 (1998) Article DOI: 10.1124/mol.54.2.322 BindingDB Entry DOI: 10.7270/Q2ZW1JGJ
Georgetown University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor (RAT)	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Curated by PDSP K_i Database									J Pharmacol Exp Ther 310: 98-107 (2004) Article DOI: 10.1124/jpet.104.066787 BindingDB Entry DOI: 10.7270/Q2XG9PQX
Georgetown University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University School of Medicine Curated by ChEMBL					Assay Description Binding affinity towards rat Nicotinic acetylcholine receptor alpha4-beta2 expressed in HEK293 cells using [3H]EB as radioligand				Bioorg Med Chem Lett 14: 1845-8 (2004) Article DOI: 10.1016/j.bmcl.2003.09.105 BindingDB Entry DOI: 10.7270/Q2TB17G2
Georgetown University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Curated by PDSP K_i Database									J Pharmacol Exp Ther 310: 98-107 (2004) Article DOI: 10.1124/jpet.104.066787 BindingDB Entry DOI: 10.7270/Q2XG9PQX
Georgetown University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor (RAT)	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	PubMed	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Curated by PDSP K_i Database									Mol Pharmacol 39: 9-12 (1991) BindingDB Entry DOI: 10.7270/Q23T9FPK
Georgetown University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	PubMed	640	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description In vitro binding affinity for muscarinic M1 receptor by displacing [3H]-Pirenzepine binding on rat brain homogenate.				J Med Chem 37: 4085-99 (1995) BindingDB Entry DOI: 10.7270/Q21N8066
H. Lundbeck A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor (RAT)	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	PubMed	671	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Curated by PDSP K_i Database									Mol Pharmacol 48: 280-7 (1995) BindingDB Entry DOI: 10.7270/Q2280648
Georgetown University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (RAT)	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NIDDK Curated by ChEMBL					Assay Description Displacement of [3H]NMS from rat M3'(3C)-Xa receptor F92C/F550C mutant expressed in african green monkey COS7 cells				J Biol Chem 282: 26284-93 (2007) Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR
NIDDK Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Mus musculus)	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	739	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Toledo Curated by ChEMBL					Assay Description Binding affinity (high) of [3H](R)-QNB binding to Muscarinic acetylcholine receptor M1 expressed in A9 L cell line in the absence of 300 uM GTP-gamma...				J Med Chem 40: 1230-46 (1997) Article DOI: 10.1021/jm960467d BindingDB Entry DOI: 10.7270/Q28916HS
The University of Toledo Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Homo sapiens (Human))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	750	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Milano Curated by ChEMBL					Assay Description Binding affinity to alpha4beta2 nAChR (unknown origin)				Bioorg Med Chem Lett 23: 6481-5 (2013) Article DOI: 10.1016/j.bmcl.2013.09.023 BindingDB Entry DOI: 10.7270/Q22V2HKF
Universit£ di Milano Curated by ChEMBL					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor (RAT)	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	750	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by PDSP K_i Database									Mol Pharmacol 64: 865-75 (2003) Article DOI: 10.1124/mol.64.4.865 BindingDB Entry DOI: 10.7270/Q2RX99PV
					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor (RAT)	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	PubMed	838	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Curated by PDSP K_i Database									J Pharmacol Exp Ther 282: 445-51 (1997) BindingDB Entry DOI: 10.7270/Q2222S97
Georgetown University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-2 (Rattus norvegicus (Rat))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	930	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Curated by PDSP K_i Database									J Pharmacol Exp Ther 310: 98-107 (2004) Article DOI: 10.1124/jpet.104.066787 BindingDB Entry DOI: 10.7270/Q2XG9PQX
Georgetown University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (RAT)	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	990	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NIDDK Curated by ChEMBL					Assay Description Displacement of [3H]NMS from rat M3'(3C)-Xa receptor F92C/R551C mutant expressed in african green monkey COS7 cells				J Biol Chem 282: 26284-93 (2007) Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR
NIDDK Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (RAT)	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	1.04E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NIDDK Curated by ChEMBL					Assay Description Displacement of [3H]NMS from rat M3'(3C)-Xa receptor F92C/T549C mutant expressed in african green monkey COS7 cells				J Biol Chem 282: 26284-93 (2007) Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR
NIDDK Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3 (Rattus norvegicus (Rat))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Curated by PDSP K_i Database									J Pharmacol Exp Ther 310: 98-107 (2004) Article DOI: 10.1124/jpet.104.066787 BindingDB Entry DOI: 10.7270/Q2XG9PQX
Georgetown University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Curated by PDSP K_i Database									J Pharmacol Exp Ther 310: 98-107 (2004) Article DOI: 10.1124/jpet.104.066787 BindingDB Entry DOI: 10.7270/Q2XG9PQX
Georgetown University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-2 (Rattus norvegicus (Rat))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University School of Medicine Curated by ChEMBL					Assay Description Binding affinity towards rat Nicotinic acetylcholine receptor alpha4-beta4 expressed in HEK293 cells using [3H]EB as radioligand				Bioorg Med Chem Lett 14: 1845-8 (2004) Article DOI: 10.1016/j.bmcl.2003.09.105 BindingDB Entry DOI: 10.7270/Q2TB17G2
Georgetown University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium \| (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human cloned muscarinic M2 receptor expressed in CHO cells				Bioorg Med Chem Lett 18: 614-8 (2008) Checked by Author Article DOI: 10.1016/j.bmcl.2007.11.073 BindingDB Entry DOI: 10.7270/Q2XP76FV
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair

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