BDBM50004789 3-[8,13-Bis-(2-acetoxy-ethyl)-18-(2-carboxy-ethyl)-3,7,12,17-tetramethyl-22,24-dihydro-porphin-2-yl]-propionic acid::CHEMBL324788

SMILES: Cc1c(CCC(O)=O)c2cc3nc(cc4[nH]c(cc5[nH]c(cc1n2)c(C)c5CCOC(=O)C1=CC1)c(C)c4CCOC(=O)C1=CC1)c(C)c3CCC(O)=O

InChI Key: InChIKey=XHZTUBRILXNMST-YAUQGLDISA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50004789   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 2 pol protein (Human immunodeficiency virus 2)	BDBM50004789 (3-[8,13-Bis-(2-acetoxy-ethyl)-18-(2-carboxy-ethyl)...) Show SMILES Cc1c(CCC(O)=O)c2cc3nc(cc4[nH]c(cc5[nH]c(cc1n2)c(C)c5CCOC(=O)C1=CC1)c(C)c4CCOC(=O)C1=CC1)c(C)c3CCC(O)=O |t:35,48| Show InChI InChI=1S/C42H42N4O8/c1-21-27(9-11-39(47)48)37-20-38-28(10-12-40(49)50)22(2)33(46-38)18-36-30(14-16-54-42(52)26-7-8-26)24(4)34(45-36)19-35-29(13-15-53-41(51)25-5-6-25)23(3)32(43-35)17-31(21)44-37/h5,7,17-20,43,45H,6,8-16H2,1-4H3,(H,47,48)(H,49,50)/b31-17-,32-17-,33-18-,34-19-,35-19-,36-18-,37-20-,38-20-	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of HIV-2 protease in 5%DMSO				J Med Chem 35: 3426-8 (1992) BindingDB Entry DOI: 10.7270/Q27W6CTB
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 protease (Human immunodeficiency virus type 1)	BDBM50004789 (3-[8,13-Bis-(2-acetoxy-ethyl)-18-(2-carboxy-ethyl)...) Show SMILES Cc1c(CCC(O)=O)c2cc3nc(cc4[nH]c(cc5[nH]c(cc1n2)c(C)c5CCOC(=O)C1=CC1)c(C)c4CCOC(=O)C1=CC1)c(C)c3CCC(O)=O |t:35,48| Show InChI InChI=1S/C42H42N4O8/c1-21-27(9-11-39(47)48)37-20-38-28(10-12-40(49)50)22(2)33(46-38)18-36-30(14-16-54-42(52)26-7-8-26)24(4)34(45-36)19-35-29(13-15-53-41(51)25-5-6-25)23(3)32(43-35)17-31(21)44-37/h5,7,17-20,43,45H,6,8-16H2,1-4H3,(H,47,48)(H,49,50)/b31-17-,32-17-,33-18-,34-19-,35-19-,36-18-,37-20-,38-20-	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	275	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of HIV-1 protease in 5%DMSO				J Med Chem 35: 3426-8 (1992) BindingDB Entry DOI: 10.7270/Q27W6CTB
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 protease (Human immunodeficiency virus type 1)	BDBM50004789 (3-[8,13-Bis-(2-acetoxy-ethyl)-18-(2-carboxy-ethyl)...) Show SMILES Cc1c(CCC(O)=O)c2cc3nc(cc4[nH]c(cc5[nH]c(cc1n2)c(C)c5CCOC(=O)C1=CC1)c(C)c4CCOC(=O)C1=CC1)c(C)c3CCC(O)=O |t:35,48| Show InChI InChI=1S/C42H42N4O8/c1-21-27(9-11-39(47)48)37-20-38-28(10-12-40(49)50)22(2)33(46-38)18-36-30(14-16-54-42(52)26-7-8-26)24(4)34(45-36)19-35-29(13-15-53-41(51)25-5-6-25)23(3)32(43-35)17-31(21)44-37/h5,7,17-20,43,45H,6,8-16H2,1-4H3,(H,47,48)(H,49,50)/b31-17-,32-17-,33-18-,34-19-,35-19-,36-18-,37-20-,38-20-	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	<5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of HIV-1 protease in 5%DMSO				J Med Chem 35: 3426-8 (1992) BindingDB Entry DOI: 10.7270/Q27W6CTB
					More data for this Ligand-Target Pair