BindingDB PrimarySearch

BDBM50004863 (+/-)-trans-ACPD::(1S,3S)-1-Amino-cyclopentane-1,3-dicarboxylic acid::(1S,3S)-1-aminocyclopentane-1,3-dicarboxylic acid::1-Amino-cyclopentane-1,3-dicarboxylic acid (APCD)::1-Amino-cyclopentane-1,3-dicarboxylic acid(cis-(1S,3S)-ACPD)::1R,3R-ACPD::1R,3S-ACPD::1S, 3R-ACPD::CHEMBL29726

SMILES: N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O

InChI Key: InChIKey=YFYNOWXBIBKGHB-FFWSUHOLSA-N

Data: 30 KI 9 EC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 39 hits for monomerid = 50004863
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	9.33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by PDSP K_i Database									J Neurochem 71: 2558-64 (1998) Article DOI: 10.1046/j.1471-4159.1998.71062558.x BindingDB Entry DOI: 10.7270/Q25D8QCZ
F. Hoffmann-La Roche Ltd. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by PDSP K_i Database									Mol Pharmacol 53: 228-33 (1998) BindingDB Entry DOI: 10.7270/Q2MP51T5
F. Hoffmann-La Roche Ltd. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Curated by PDSP K_i Database									J Neurochem 75: 2590-601 (2000) Article DOI: 10.1046/j.1471-4159.2000.0752590.x BindingDB Entry DOI: 10.7270/Q2J67FGZ
F. Hoffmann-La Roche Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Curated by PDSP K_i Database									J Neurochem 75: 2590-601 (2000) Article DOI: 10.1046/j.1471-4159.2000.0752590.x BindingDB Entry DOI: 10.7270/Q2J67FGZ
F. Hoffmann-La Roche Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by PDSP K_i Database									Annu Rev Pharmacol Toxicol 37: 205-37 (1997) Article DOI: 10.1146/annurev.pharmtox.37.1.205 BindingDB Entry DOI: 10.7270/Q2M043ZH
Emory University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
metabotropic glutamate 5a (PORCINE)	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS CCIPE Curated by PDSP K_i Database									J Neurosci 15: 3970-81 (1995) BindingDB Entry DOI: 10.7270/Q2WM1BXH
CNRS CCIPE Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNS Research Curated by PDSP K_i Database									J Neurochem 67: 58-63 (1996) Article DOI: 10.1046/j.1471-4159.1996.67010058.x BindingDB Entry DOI: 10.7270/Q2P55M1B
CNS Research Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
metabotropic glutamate 5a (PORCINE)	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS CCIPE Curated by PDSP K_i Database									J Neurosci 15: 3970-81 (1995) BindingDB Entry DOI: 10.7270/Q2WM1BXH
CNRS CCIPE Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by PDSP K_i Database									Annu Rev Pharmacol Toxicol 37: 205-37 (1997) Article DOI: 10.1146/annurev.pharmtox.37.1.205 BindingDB Entry DOI: 10.7270/Q2M043ZH
Emory University Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic Glutamate 1a (PORCINE)	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB Reactome pathway UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS CCIPE Curated by PDSP K_i Database									J Neurosci 15: 3970-81 (1995) BindingDB Entry DOI: 10.7270/Q2WM1BXH
CNRS CCIPE Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UPR Centre Curated by PDSP K_i Database									Mol Pharmacol 50: 923-30 (1996) BindingDB Entry DOI: 10.7270/Q2M61HS5
UPR Centre Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UPR Centre Curated by PDSP K_i Database									Mol Pharmacol 50: 923-30 (1996) BindingDB Entry DOI: 10.7270/Q2M61HS5
UPR Centre Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UPR Centre Curated by PDSP K_i Database									Mol Pharmacol 50: 923-30 (1996) BindingDB Entry DOI: 10.7270/Q2M61HS5
UPR Centre Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGlu4) (Rattus norvegicus (Rat))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UPR Centre Curated by PDSP K_i Database									Mol Pharmacol 50: 923-30 (1996) BindingDB Entry DOI: 10.7270/Q2M61HS5
UPR Centre Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGlu4) (Rattus norvegicus (Rat))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UPR Centre Curated by PDSP K_i Database									Mol Pharmacol 50: 923-30 (1996) BindingDB Entry DOI: 10.7270/Q2M61HS5
UPR Centre Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNS Research Curated by PDSP K_i Database									J Neurochem 67: 58-63 (1996) Article DOI: 10.1046/j.1471-4159.1996.67010058.x BindingDB Entry DOI: 10.7270/Q2P55M1B
CNS Research Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNS Research Curated by PDSP K_i Database									J Neurochem 67: 58-63 (1996) Article DOI: 10.1046/j.1471-4159.1996.67010058.x BindingDB Entry DOI: 10.7270/Q2P55M1B
CNS Research Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNS Research Curated by PDSP K_i Database									J Neurochem 67: 58-63 (1996) Article DOI: 10.1046/j.1471-4159.1996.67010058.x BindingDB Entry DOI: 10.7270/Q2P55M1B
CNS Research Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 6 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by PDSP K_i Database									Annu Rev Pharmacol Toxicol 37: 205-37 (1997) Article DOI: 10.1146/annurev.pharmtox.37.1.205 BindingDB Entry DOI: 10.7270/Q2M043ZH
Emory University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGluR4) (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by PDSP K_i Database									Annu Rev Pharmacol Toxicol 37: 205-37 (1997) Article DOI: 10.1146/annurev.pharmtox.37.1.205 BindingDB Entry DOI: 10.7270/Q2M043ZH
Emory University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by PDSP K_i Database									Annu Rev Pharmacol Toxicol 37: 205-37 (1997) Article DOI: 10.1146/annurev.pharmtox.37.1.205 BindingDB Entry DOI: 10.7270/Q2M043ZH
Emory University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
metabotropic glutamate 5a (PORCINE)	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS CCIPE Curated by PDSP K_i Database									J Neurosci 15: 3970-81 (1995) BindingDB Entry DOI: 10.7270/Q2WM1BXH
CNRS CCIPE Curated by PDSP K_i Database					More data for this Ligand-Target Pair
metabotropic glutamate 5a (PORCINE)	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS CCIPE Curated by PDSP K_i Database									J Neurosci 15: 3970-81 (1995) BindingDB Entry DOI: 10.7270/Q2WM1BXH
CNRS CCIPE Curated by PDSP K_i Database					More data for this Ligand-Target Pair
metabotropic glutamate 5a (PORCINE)	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS CCIPE Curated by PDSP K_i Database									J Neurosci 15: 3970-81 (1995) BindingDB Entry DOI: 10.7270/Q2WM1BXH
CNRS CCIPE Curated by PDSP K_i Database					More data for this Ligand-Target Pair
metabotropic glutamate 5a (PORCINE)	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS CCIPE Curated by PDSP K_i Database									J Neurosci 15: 3970-81 (1995) BindingDB Entry DOI: 10.7270/Q2WM1BXH
CNRS CCIPE Curated by PDSP K_i Database					More data for this Ligand-Target Pair
metabotropic glutamate 5a (PORCINE)	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS CCIPE Curated by PDSP K_i Database									J Neurosci 15: 3970-81 (1995) BindingDB Entry DOI: 10.7270/Q2WM1BXH
CNRS CCIPE Curated by PDSP K_i Database					More data for this Ligand-Target Pair
metabotropic glutamate 5a (PORCINE)	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS CCIPE Curated by PDSP K_i Database									J Neurosci 15: 3970-81 (1995) BindingDB Entry DOI: 10.7270/Q2WM1BXH
CNRS CCIPE Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic Glutamate 1a (PORCINE)	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB Reactome pathway UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS CCIPE Curated by PDSP K_i Database									J Neurosci 15: 3970-81 (1995) BindingDB Entry DOI: 10.7270/Q2WM1BXH
CNRS CCIPE Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic Glutamate 1a (PORCINE)	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB Reactome pathway UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS CCIPE Curated by PDSP K_i Database									J Neurosci 15: 3970-81 (1995) BindingDB Entry DOI: 10.7270/Q2WM1BXH
CNRS CCIPE Curated by PDSP K_i Database					More data for this Ligand-Target Pair
GRIA3 (RAT)	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by PDSP K_i Database									J Pharmacol Exp Ther 298: 453-60 (2001) Article DOI: 10.1016/j.bioorg.2016.02.004 BindingDB Entry DOI: 10.7270/Q2V986M2
Eli Lilly and Company Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a
Université René Descartes-Paris V Curated by ChEMBL					Assay Description Agonist activity against Metabotropic glutamate receptor 1 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulatio...				J Med Chem 40: 3119-29 (1997) Article DOI: 10.1021/jm970207b BindingDB Entry DOI: 10.7270/Q200016Q
Université René Descartes-Paris V Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a
Université René Descartes-Paris V Curated by ChEMBL					Assay Description Agonist activity against Metabotropic glutamate receptor 2 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulatio...				J Med Chem 40: 3119-29 (1997) Article DOI: 10.1021/jm970207b BindingDB Entry DOI: 10.7270/Q200016Q
Université René Descartes-Paris V Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGluR4) (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.80E+4	n/a	n/a	n/a	n/a
Université René Descartes-Paris V Curated by ChEMBL					Assay Description Agonist activity against Metabotropic glutamate receptor 4 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulatio...				J Med Chem 40: 3119-29 (1997) Article DOI: 10.1021/jm970207b BindingDB Entry DOI: 10.7270/Q200016Q
Université René Descartes-Paris V Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Compound was tested for the inhibition of Metabotropic glutamate receptor 3 (mGluR3)				J Med Chem 41: 1641-50 (1998) Article DOI: 10.1021/jm970719q BindingDB Entry DOI: 10.7270/Q27945BZ
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 4 (mGlu4) (Rattus norvegicus (Rat))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					Assay Description Stimulation of [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells; Inacti...				J Med Chem 48: 2534-47 (2005) Article DOI: 10.1021/jm049092j BindingDB Entry DOI: 10.7270/Q23X87FM
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Compound was tested for the inhibition of metabotropic glutamate receptor 2 (mGluR2).				J Med Chem 41: 1641-50 (1998) Article DOI: 10.1021/jm970719q BindingDB Entry DOI: 10.7270/Q27945BZ
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Compound was tested for the inhibition of Metabotropic glutamate receptor 5				J Med Chem 41: 1641-50 (1998) Article DOI: 10.1021/jm970719q BindingDB Entry DOI: 10.7270/Q27945BZ
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGluR4) (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Compound was tested for the inhibition of Metabotropic glutamate receptor 4				J Med Chem 41: 1641-50 (1998) Article DOI: 10.1021/jm970719q BindingDB Entry DOI: 10.7270/Q27945BZ
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Compound was tested for the inhibition of Metabotropic glutamate receptor 1				J Med Chem 41: 1641-50 (1998) Article DOI: 10.1021/jm970719q BindingDB Entry DOI: 10.7270/Q27945BZ
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair