Found 12 hits for monomerid = 50004899 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50004899
((1R,2S)-2-((S)-Amino-carboxy-methyl)-cyclopropanec...)Show InChI InChI=1S/C6H9NO4/c7-4(6(10)11)2-1-3(2)5(8)9/h2-4H,1,7H2,(H,8,9)(H,10,11)/t2-,3+,4-/m0/s1 | PDB
UniProtKB/SwissProt
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| Article PubMed
| 3.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNS Research
Curated by PDSP Ki Database
| |
J Neurochem 67: 58-63 (1996)
Article DOI: 10.1046/j.1471-4159.1996.67010058.x BindingDB Entry DOI: 10.7270/Q2P55M1B |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50004899
((1R,2S)-2-((S)-Amino-carboxy-methyl)-cyclopropanec...)Show InChI InChI=1S/C6H9NO4/c7-4(6(10)11)2-1-3(2)5(8)9/h2-4H,1,7H2,(H,8,9)(H,10,11)/t2-,3+,4-/m0/s1 | PDB
UniProtKB/SwissProt
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| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNS Research
Curated by PDSP Ki Database
| |
J Neurochem 67: 58-63 (1996)
Article DOI: 10.1046/j.1471-4159.1996.67010058.x BindingDB Entry DOI: 10.7270/Q2P55M1B |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 3
(Homo sapiens (Human)) | BDBM50004899
((1R,2S)-2-((S)-Amino-carboxy-methyl)-cyclopropanec...)Show InChI InChI=1S/C6H9NO4/c7-4(6(10)11)2-1-3(2)5(8)9/h2-4H,1,7H2,(H,8,9)(H,10,11)/t2-,3+,4-/m0/s1 | PDB
UniProtKB/SwissProt
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| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNS Research
Curated by PDSP Ki Database
| |
J Neurochem 67: 58-63 (1996)
Article DOI: 10.1046/j.1471-4159.1996.67010058.x BindingDB Entry DOI: 10.7270/Q2P55M1B |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 3
(Homo sapiens (Human)) | BDBM50004899
((1R,2S)-2-((S)-Amino-carboxy-methyl)-cyclopropanec...)Show InChI InChI=1S/C6H9NO4/c7-4(6(10)11)2-1-3(2)5(8)9/h2-4H,1,7H2,(H,8,9)(H,10,11)/t2-,3+,4-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
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| Article PubMed
| 380 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNS Research
Curated by PDSP Ki Database
| |
J Neurochem 67: 58-63 (1996)
Article DOI: 10.1046/j.1471-4159.1996.67010058.x BindingDB Entry DOI: 10.7270/Q2P55M1B |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 3
(Homo sapiens (Human)) | BDBM50004899
((1R,2S)-2-((S)-Amino-carboxy-methyl)-cyclopropanec...)Show InChI InChI=1S/C6H9NO4/c7-4(6(10)11)2-1-3(2)5(8)9/h2-4H,1,7H2,(H,8,9)(H,10,11)/t2-,3+,4-/m0/s1 | PDB
UniProtKB/SwissProt
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| Article PubMed
| 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNS Research
Curated by PDSP Ki Database
| |
J Neurochem 67: 58-63 (1996)
Article DOI: 10.1046/j.1471-4159.1996.67010058.x BindingDB Entry DOI: 10.7270/Q2P55M1B |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 2
(Homo sapiens (Human)) | BDBM50004899
((1R,2S)-2-((S)-Amino-carboxy-methyl)-cyclopropanec...)Show InChI InChI=1S/C6H9NO4/c7-4(6(10)11)2-1-3(2)5(8)9/h2-4H,1,7H2,(H,8,9)(H,10,11)/t2-,3+,4-/m0/s1 | PDB
UniProtKB/SwissProt
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| Article PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Berne
Curated by ChEMBL
| Assay Description Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation counting |
J Med Chem 53: 7236-50 (2010)
Article DOI: 10.1021/jm100959g BindingDB Entry DOI: 10.7270/Q27081NR |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50004899
((1R,2S)-2-((S)-Amino-carboxy-methyl)-cyclopropanec...)Show InChI InChI=1S/C6H9NO4/c7-4(6(10)11)2-1-3(2)5(8)9/h2-4H,1,7H2,(H,8,9)(H,10,11)/t2-,3+,4-/m0/s1 | PDB
UniProtKB/SwissProt
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| PubMed
| 70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd.
Curated by PDSP Ki Database
| |
Mol Pharmacol 53: 228-33 (1998)
BindingDB Entry DOI: 10.7270/Q2MP51T5 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50004899
((1R,2S)-2-((S)-Amino-carboxy-methyl)-cyclopropanec...)Show InChI InChI=1S/C6H9NO4/c7-4(6(10)11)2-1-3(2)5(8)9/h2-4H,1,7H2,(H,8,9)(H,10,11)/t2-,3+,4-/m0/s1 | PDB
UniProtKB/SwissProt
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| Article PubMed
| 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche
Curated by PDSP Ki Database
| |
J Neurochem 75: 2590-601 (2000)
Article DOI: 10.1046/j.1471-4159.2000.0752590.x BindingDB Entry DOI: 10.7270/Q2J67FGZ |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50004899
((1R,2S)-2-((S)-Amino-carboxy-methyl)-cyclopropanec...)Show InChI InChI=1S/C6H9NO4/c7-4(6(10)11)2-1-3(2)5(8)9/h2-4H,1,7H2,(H,8,9)(H,10,11)/t2-,3+,4-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
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| 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche
Curated by PDSP Ki Database
| |
J Neurochem 75: 2590-601 (2000)
Article DOI: 10.1046/j.1471-4159.2000.0752590.x BindingDB Entry DOI: 10.7270/Q2J67FGZ |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50004899
((1R,2S)-2-((S)-Amino-carboxy-methyl)-cyclopropanec...)Show InChI InChI=1S/C6H9NO4/c7-4(6(10)11)2-1-3(2)5(8)9/h2-4H,1,7H2,(H,8,9)(H,10,11)/t2-,3+,4-/m0/s1 | PDB
UniProtKB/SwissProt
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| Article PubMed
| 0.378 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd.
Curated by PDSP Ki Database
| |
J Neurochem 71: 2558-64 (1998)
Article DOI: 10.1046/j.1471-4159.1998.71062558.x BindingDB Entry DOI: 10.7270/Q25D8QCZ |
More data for this Ligand-Target Pair | |
Glutamate receptor 3
(RAT) | BDBM50004899
((1R,2S)-2-((S)-Amino-carboxy-methyl)-cyclopropanec...)Show InChI InChI=1S/C6H9NO4/c7-4(6(10)11)2-1-3(2)5(8)9/h2-4H,1,7H2,(H,8,9)(H,10,11)/t2-,3+,4-/m0/s1 | PDB
UniProtKB/SwissProt
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| 334 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 298: 453-60 (2001)
BindingDB Entry DOI: 10.7270/Q2V986M2 |
More data for this Ligand-Target Pair | |
Glutamate receptor ionotropic, NMDA 1
(RAT) | BDBM50004899
((1R,2S)-2-((S)-Amino-carboxy-methyl)-cyclopropanec...)Show InChI InChI=1S/C6H9NO4/c7-4(6(10)11)2-1-3(2)5(8)9/h2-4H,1,7H2,(H,8,9)(H,10,11)/t2-,3+,4-/m0/s1 | PDB
UniProtKB/SwissProt
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| Article PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Suntory Institute for Bioorganic Research
Curated by PDSP Ki Database
| |
Mol Pharmacol 53: 195-201 (1998)
Article DOI: 10.1124/mol.53.2.195 BindingDB Entry DOI: 10.7270/Q2RF5SJH |
More data for this Ligand-Target Pair | |