BDBM50005215 CHEMBL3109274
SMILES: CCS(=O)(=O)c1ccc(OC)c(Nc2ncc(o2)-c2cc(cc(c2)-c2ccccn2)-c2ccccn2)c1
InChI Key: InChIKey=HTPMEGBLXVAKBQ-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50005215 (CHEMBL3109274) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Comenius University Curated by ChEMBL | Assay Description Inhibition of GST-tagged recombinant human VEGFR2 expressed in Sf9 cells by radiometric assay | Eur J Med Chem 72: 146-59 (2014) Article DOI: 10.1016/j.ejmech.2013.11.023 BindingDB Entry DOI: 10.7270/Q2K93919 | |||||||||||
More data for this Ligand-Target Pair |