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BDBM50005249 2-(2,5-Dimethoxy-4-propyl-phenyl)-1-methyl-ethylamine::2-(2,5-Dimethoxy-4-propyl-phenyl)-1-methyl-ethylamine(DOPR)::CHEMBL8569::DOPR
SMILES: CCCc1cc(OC)c(CC(C)N)cc1OC
InChI Key: InChIKey=UEEAUFJYLUJWQJ-UHFFFAOYSA-N
Data: 9 KI
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50005249 (2-(2,5-Dimethoxy-4-propyl-phenyl)-1-methyl-ethylam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by PDSP Ki Database | Naunyn Schmiedebergs Arch Pharmacol 359: 1-6 (1999) Article DOI: 10.1007/pl00005315 BindingDB Entry DOI: 10.7270/Q2862F09 | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50005249 (2-(2,5-Dimethoxy-4-propyl-phenyl)-1-methyl-ethylam...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by PDSP Ki Database | Naunyn Schmiedebergs Arch Pharmacol 359: 1-6 (1999) Article DOI: 10.1007/pl00005315 BindingDB Entry DOI: 10.7270/Q2862F09 | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat)) | BDBM50005249 (2-(2,5-Dimethoxy-4-propyl-phenyl)-1-methyl-ethylam...) | KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affinity towards 5-hydroxytryptamine 1C receptor from frontal cortical regions of male Sprague-Dawley rat homogenates, using [3H]mesulergine ... | J Med Chem 35: 734-40 (1992) BindingDB Entry DOI: 10.7270/Q29K4BV4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50005249 (2-(2,5-Dimethoxy-4-propyl-phenyl)-1-methyl-ethylam...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 54.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by PDSP Ki Database | Naunyn Schmiedebergs Arch Pharmacol 359: 1-6 (1999) Article DOI: 10.1007/pl00005315 BindingDB Entry DOI: 10.7270/Q2862F09 | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...) | BDBM50005249 (2-(2,5-Dimethoxy-4-propyl-phenyl)-1-methyl-ethylam...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 69 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affinity towards 5-hydroxytryptamine 2 receptor from frontal cortical regions of male Sprague-Dawley rat homogenates, using [3H]ketanserin as... | J Med Chem 35: 734-40 (1992) BindingDB Entry DOI: 10.7270/Q29K4BV4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...) | BDBM50005249 (2-(2,5-Dimethoxy-4-propyl-phenyl)-1-methyl-ethylam...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 69 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor of rat frontal cortex using [3H]ketanserin radioligand | J Med Chem 33: 1032-6 (1990) BindingDB Entry DOI: 10.7270/Q2319Z37 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...) | BDBM50005249 (2-(2,5-Dimethoxy-4-propyl-phenyl)-1-methyl-ethylam...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 69 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity to rat cortical membranes at 5-hydroxytryptamine 2 (5-HT2) receptor using [3H]KET as a radioligand | J Med Chem 30: 1-12 (1987) BindingDB Entry DOI: 10.7270/Q29K4BS7 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serotonin receptor 2a and 2b (5HT2A and 5HT2B) (RAT) | BDBM50005249 (2-(2,5-Dimethoxy-4-propyl-phenyl)-1-methyl-ethylam...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 115 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by PDSP Ki Database | Naunyn Schmiedebergs Arch Pharmacol 359: 1-6 (1999) Article DOI: 10.1007/pl00005315 BindingDB Entry DOI: 10.7270/Q2862F09 | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serotonin 1 (5-HT1) receptor (RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...) | BDBM50005249 (2-(2,5-Dimethoxy-4-propyl-phenyl)-1-methyl-ethylam...) | PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Evaluated for binding affinity towards rat cortical membranes at 5-hydroxytryptamine 1 receptor binding site by using [3H]-5-HT as a radioligand. | J Med Chem 30: 1-12 (1987) BindingDB Entry DOI: 10.7270/Q29K4BS7 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
