BDBM50005281 CHEMBL3114513

SMILES: Clc1cccc(CNC(=O)c2nc3c(cccc3[nH]2)-c2ccccc2)c1

InChI Key: InChIKey=MOSIJYALUGKDKL-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50005281   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50005281 (CHEMBL3114513) Show SMILES Clc1cccc(CNC(=O)c2nc3c(cccc3[nH]2)-c2ccccc2)c1 Show InChI InChI=1S/C21H16ClN3O/c22-16-9-4-6-14(12-16)13-23-21(26)20-24-18-11-5-10-17(19(18)25-20)15-7-2-1-3-8-15/h1-12H,13H2,(H,23,26)(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	165	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as forskolin-induced cAMP accumulation after 1 hr				Bioorg Med Chem Lett 24: 1218-21 (2014) Article DOI: 10.1016/j.bmcl.2013.12.068 BindingDB Entry DOI: 10.7270/Q2FJ2J9K
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50005281 (CHEMBL3114513) Show SMILES Clc1cccc(CNC(=O)c2nc3c(cccc3[nH]2)-c2ccccc2)c1 Show InChI InChI=1S/C21H16ClN3O/c22-16-9-4-6-14(12-16)13-23-21(26)20-24-18-11-5-10-17(19(18)25-20)15-7-2-1-3-8-15/h1-12H,13H2,(H,23,26)(H,24,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.70E+4	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as forskolin-induced cAMP accumulation after 1 hr				Bioorg Med Chem Lett 24: 1218-21 (2014) Article DOI: 10.1016/j.bmcl.2013.12.068 BindingDB Entry DOI: 10.7270/Q2FJ2J9K
					More data for this Ligand-Target Pair